D-Fructose-6-phosphate disodium hydrate
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D-Fructose 6-phosphate disodium hydrate is an endogenous metabolite. D-Fructose 6-phosphate disodium hydrate can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate disodium hydrate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate disodium hydrate can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate disodium hydrate can be used to study Lewy body dementia.
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- CAS No.: 918149-30-1
- Formula: C6H15Na2O11P
- Molecular Weight:340.13
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Endogenous Metabolite Isoforms
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Biological Activity
D-Fructose-6-phosphate (3.2 mM; room temperature) disodium hydrate can detect transaldolase TAL activity[3].
D-Fructose-6-phosphate (10 mM; incubation at 37°C for 60 min) disodium hydrate can complete the detection of glucosamine-6-phosphate synthase activity[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 918149-30-1
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Appearance Solid
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Molecular Weight 340.13
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Formula C6H15Na2O11P
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SMILES
OCC([C@H]([C@@H]([C@@H](COP(O[Na])(O[Na])=O)O)O)O)=O.O.O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
References
[1]. Lee JH, et al. Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate D-fructose 6-phosphate. Biochemistry. 2001 Jul 3;40(26):7799-805. [Content Brief]
[2]. Hardie DG, et al. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol. 2012 Mar 22;13(4):251-62. [Content Brief]
[3]. Puskas F, et al. Stimulation of the pentose phosphate pathway and glutathione levels by dehydroascorbate, the oxidized form of vitamin C. FASEB J. 2000 Jul;14(10):1352-61. [Content Brief]
[4]. Hiramatsu M, et al. Suppression by thyroid hormones of glucosamine-6-phosphate synthetase activity in rat sublingual glands. Arch Oral Biol. 1984;29(10):849-51. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)