1. Anti-infection
    Apoptosis
  2. Bacterial
    Apoptosis
  3. 3-Nitropropanoic acid

3-Nitropropanoic acid (Synonyms: β-Nitropropionic acid; Bovinocidin)

Cat. No.: HY-W012875 Purity: 99.46%
Handling Instructions

3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM.

For research use only. We do not sell to patients.

3-Nitropropanoic acid Chemical Structure

3-Nitropropanoic acid Chemical Structure

CAS No. : 504-88-1

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Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1  mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
500 mg USD 80 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM[1][2].

IC50 & Target

succinate dehydrogenase[1]

Molecular Weight

119.08

Formula

C₃H₅NO₄

CAS No.

504-88-1

SMILES

O=C(O)CC[N+]([O-])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 130 mg/mL (1091.70 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.3977 mL 41.9886 mL 83.9772 mL
5 mM 1.6795 mL 8.3977 mL 16.7954 mL
10 mM 0.8398 mL 4.1989 mL 8.3977 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.17 mg/mL (18.22 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.17 mg/mL (18.22 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.17 mg/mL (18.22 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.46%

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

3-Nitropropanoic acidβ-Nitropropionic acidBovinocidinBacterialApoptosisInhibitorinhibitorinhibit

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3-Nitropropanoic acid
Cat. No.:
HY-W012875
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