Oligomycin
Based on 106 publication(s) in Google Scholar
Oligomycin, an antifungal antibiotic, is an inhibitor of H+-ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells.
For research use only. We do not sell to patients.
- Purity: 98.64%
- CAS No.: 1404-19-9
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) Oligomycin
More- Cell. 2024 Apr 25;187(9):2269-2287.e16. [Abstract]
- Cell Metab. 2026 May 5;38(5):963-980.e12. [Abstract]
- Nat Immunol. 2024 Jun;25(6):981-993. [Abstract]
- Nat Metab. 2026 Jan;8(1):177-195. [Abstract]
- Cell Stem Cell. 2025 Apr 3;32(4):547-563.e7. [Abstract]
- Cell Mol Immunol. 2024 Jun;21(6):546-560. [Abstract]
- Nat Microbiol. 2025 Oct;10(10):2521-2536. [Abstract]
- Nat Cell Biol. 2026 Apr;28(4):707-724. [Abstract]
- Cancer Res. 2023 Dec 15;83(24):4063-4079. [Abstract]
- Mol Cell. 2022 May 19;82(10):1821-1835.e6. [Abstract]
- Nat Commun. 2026 Jan 31;17(1):2227. [Abstract]
- Nat Commun. 2024 Oct 8;15(1):8723. [Abstract]
- Nat Commun. 2022 Jun 17;13(1):3486. [Abstract]
- J Am Chem Soc. 2023 Oct 18;145(41):22433-22441. [Abstract]
- Cell Death Differ. 2025 Oct 7. [Abstract]
- Autophagy. 2025 Dec 26:1-18. [Abstract]
- Autophagy. 2025 Mar;21(3):548-564. [Abstract]
- Autophagy. 2024 Nov;20(11):2556-2570. [Abstract]
- Adv Sci (Weinh). 2025 Oct 13:e09383. [Abstract]
- Adv Sci (Weinh). 2025 Apr 13:e2413376. [Abstract]
- J Adv Res. 2025 Jan 2:S2090-1232(24)00623-4. [Abstract]
- Biomaterials. 2025 May 5:322:123391. [Abstract]
- Exp Mol Med. 2022 Nov;54(11):2007-2021. [Abstract]
- J Exp Clin Cancer Res. 2025 Jan 3;44(1):3. [Abstract]
- J Nanobiotechnology. 2025 Aug 12;23(1):562. [Abstract]
- Redox Biol. 2024 May 23:73:103207. [Abstract]
- Redox Biol. 2021 Jul:43:101994. [Abstract]
- Appl Phys Rev. 2026 Jan 21.
- Engineering. 2025 Nov 14.
- Engineering. 2024 Sep 6.
- EBioMedicine. 2025 Aug 15:119:105879. [Abstract]
- Pharmacol Res. 2021 Feb:164:105367. [Abstract]
- Cancer Lett. 2022 Dec 1:550:215918. [Abstract]
- Cell Death Dis. 2026 Jan 8;17(1):11. [Abstract]
- Cell Death Dis. 2025 Nov 7;16(1):805. [Abstract]
- Cell Death Dis. 2024 Mar 29;15(3):236. [Abstract]
- Cell Death Dis. 2022 Oct 26;13(10):899. [Abstract]
- Cell Death Dis. 2021 Apr 20;12(5):413. [Abstract]
- Proc Natl Acad Sci U S A. 2026 Mar 31;123(13):e2520119123. [Abstract]
- Dev Cell. 2025 Apr 18:S1534-5807(25)00206-0. [Abstract]
- Acta Pharmacol Sin. 2025 Jun 11. [Abstract]
- Phytomedicine. 2025 Dec 9:150:157684. [Abstract]
- EMBO Mol Med. 2025 Oct 13. [Abstract]
- Phytomedicine. 2024 Jul:129:155675. [Abstract]
- ACS Appl Mater Interfaces. 2025 Oct 1;17(39):54453-54465. [Abstract]
- Free Radic Biol Med. 2025 Mar 1:229:399-414. [Abstract]
- Free Radic Biol Med. 2024 Jul 9:S0891-5849(24)00552-5. [Abstract]
- Free Radic Biol Med. 2023 Mar:198:83-91. [Abstract]
- Cancer Immunol Res. 2023 Apr 3;11(4):515-529. [Abstract]
- NPJ Precis Oncol. 2025 Jun 5;9(1):163. [Abstract]
- Sens Actuators B Chem. 2025 Jul 1.
- J Transl Med. 2024 Jun 5;22(1):535. [Abstract]
- J Transl Med. 2024 Jan 18;22(1):74. [Abstract]
- J Transl Med. 2023 Sep 7;21(1):605. [Abstract]
- J Transl Med. 2023 Aug 18;21(1):553. [Abstract]
- Stem Cell Res Ther. 2025 May 4;16(1):225. [Abstract]
- Oncogene. 2024 Oct;43(44):3215-3226. [Abstract]
- Aging Cell. 2025 Oct;24(10):e70213. [Abstract]
- Cell Death Discov. 2025 Jul 2;11(1):299. [Abstract]
- Cell Death Discov. 2025 Mar 1;11(1):82. [Abstract]
- Cell Rep. 2025 Jul 30;44(8):116091. [Abstract]
- Cell Rep. 2023 Aug 28;42(9):113044. [Abstract]
- Cell Rep. 2023 Jun 6;42(6):112617. [Abstract]
- Clin Transl Med. 2022 Jan;12(1):e686. [Abstract]
- Cell Mol Life Sci. 2025 Apr 12;82(1):157. [Abstract]
- J Agric Food Chem. 2024 Jun 12;72(23):13039-13053. [Abstract]
- EMBO Rep. 2023 Nov 6;24(11):e56958. [Abstract]
- Ecotoxicol Environ Saf. 2023 Oct 1:264:115472. [Abstract]
- Front Immunol. 2022 Mar 10;13:771732. [Abstract]
- Mar Drugs. 2021 Jan 31;19(2):79. [Abstract]
- Cancer Metab. 2025 Mar 31;13(1):16. [Abstract]
- Cancer Metab. 2022 Dec 6;10(1):22. [Abstract]
- Life Sci. 2026 Apr 1:390:124256. [Abstract]
- Int J Mol Sci. 2024 Sep 29;25(19):10514. [Abstract]
- iScience. 2022 Aug 4;25(9):104844. [Abstract]
- iScience. 2021 Sep 25;24(10):103170. [Abstract]
- Virol Sin. 2025 Nov 21:S1995-820X(25)00161-0. [Abstract]
- Drug Metab Dispos. 2025 Nov;53(11):100172. [Abstract]
- J Virol. 2025 Nov 25;99(11):e0157625. [Abstract]
- Biochem Eng J. 2024 Nov.
- Expert Rev Clin Immunol. 2025 Jun 25:1-11. [Abstract]
- Int Dent J. 2024 May 27:S0020-6539(24)00125-4. [Abstract]
- Toxicol Appl Pharmacol. 2026 Feb 27:511:117776. [Abstract]
- Toxicol Appl Pharmacol. 2025 Sep 22:505:117578. [Abstract]
- Toxicol Appl Pharmacol. 2024 May:486:116951. [Abstract]
- Biochim Biophys Acta Mol Cell Biol Lipids. 2025 Apr 4:159610. [Abstract]
- Pathol Res Pract. 2026 Apr:280:156383. [Abstract]
- J Bioenerg Biomembr. 2026 Mar 18. [Abstract]
- Immunopharmacol Immunotoxicol. 2023 Jun;45(3):355-369. [Abstract]
- J Immunother. 2024 Oct 1;47(8):313-322. [Abstract]
- Free Radic Res. 2024 Jul 30:1-16. [Abstract]
- Int J Biochem Cell Biol. 2025 Oct:187:106831. [Abstract]
- Vet Microbiol. 2025 Oct:309:110695. [Abstract]
- Brain Res. 2024 Dec 24:149424. [Abstract]
- Prostate. 2025 Oct 1. [Abstract]
- Prostate. 2025 Oct 1. [Abstract]
- Toxicon. 2026 Jun 15:276:109067. [Abstract]
- Biochem Biophys Res Commun. 2023 Sep 3:671:46-57. [Abstract]
- bioRxiv. 2026 Jan 7.
- bioRxiv. 2025 Nov 4.
- SSRN. 2025 Nov 26.
- Pharmacological Research Modern Chinese Medicine. 2025 Sep 20;17:100693.
- bioRxiv. 2025 April 16.
- bioRxiv. 2024 June 03.
- bioRxiv. 2024 June 27.
- Oxid Med Cell Longev. 2022 Apr 5;2022:8192552. [Abstract]
Customer Validation & Images
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All Antibiotic Isoforms
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Biological Activity
Chemical Information
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CAS No. 1404-19-9
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Appearance Solid
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Color White to off-white
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SMILES
O=C1/C=C/[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)[C@@H](O)[C@H](C)C([C@@](O)(C)[C@@H](O)[C@H](C)C/C=C/C=C/[C@H](CC)CC[C@]2([H])O[C@@]3(O[C@@H](C[C@H](O)C)[C@@H](C)CC3)[C@H]([C@@](O1)([H])[C@@H]2C)C)=O)=O.O=C4/C=C/[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)[C@@H](O)[C@H](C)C([C@@H](C)[C@@H](O)[C@H](C)C/C=C/C=C/[C@@](CC)([H])CC[C@]5([H])O[C@@]6(O[C@](C[C@H](O)C)([H])[C@@H](C)CC6)[C@H]([C@@](O4)([H])[C@@H]5C)C)=O)=O
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Structure Classification
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Initial Source
Streptomyces
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (106)
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Journal Impact Factor
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Most Recent
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Cell
2024 Apr 25;187(9):2269-2287.e16. PMID: 38608703
Oligomycin purchased from MedChemExpress. Usage Cited in: Cell. 2024 Apr 25;187(9):2269-2287.e16. [Abstract]
Abundance of BRCA2, γH2AX protein, and MG-H1 adduct formation in HeLa Kyoto cells after treatment with Oligomycin (1 μM) for 4, 24, and 48 h.
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Cell Metab
Psoriasis modulates inflammatory bowel disease risk and intestinal epithelium lipid metabolism via IL-1β-producing macrophages. [Abstract]2026 May 5;38(5):963-980.e12. PMID: 41856104 -
Nat Immunol
An IFNγ-dependent immune-endocrine circuit lowers blood glucose to potentiate the innate antiviral immune response. [Abstract]2024 Jun;25(6):981-993. PMID: 38811816 -
Nat Metab
IL-21 mediates crosstalk between T cells and NK cells during the remission of type 1 diabetes. [Abstract]2026 Jan;8(1):177-195. PMID: 41566069 -
Cell Stem Cell
Enhanced viability and functional maturity of iPSC-derived islet organoids by collagen-VI-enriched ECM scaffolds. [Abstract]2025 Apr 3;32(4):547-563.e7. PMID: 39999846 -
Cell Mol Immunol
Lkb1 orchestrates γδ T-cell metabolic and functional fitness to control IL-17-mediated autoimmune hepatitis. [Abstract]2024 Jun;21(6):546-560. PMID: 38641698 -
Nat Microbiol
Oxaloacetate sensing promotes innate immune antiviral defence against influenza virus infection. [Abstract]2025 Oct;10(10):2521-2536. PMID: 40983701 -
Nat Cell Biol
An extracellular vesicle-mediated mitochondrial transfer network critical for testosterone synthesis. [Abstract]2026 Apr;28(4):707-724. PMID: 41760931 -
Cancer Res
Fructose-induced mTORC1 Activation Promotes Pancreatic Cancer Progression through Inhibition of Autophagy. [Abstract]2023 Dec 15;83(24):4063-4079. PMID: 37738413 -
Mol Cell
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis. [Abstract]2022 May 19;82(10):1821-1835.e6. PMID: 35381197 -
Nat Commun
Microbiota-induced EI24 improves homeostasis but impedes function of alveolar macrophages via metabolic regulation. [Abstract]2026 Jan 31;17(1):2227. PMID: 41620436 -
Nat Commun
A germline-to-soma signal triggers an age-related decline of mitochondrial stress response. [Abstract]2024 Oct 8;15(1):8723. PMID: 39379393
Oligomycin purchased from MedChemExpress. Usage Cited in: Nat Commun. 2024 Oct 8;15(1):8723. [Abstract]
qRT-PCR analysis of Chop and Asns mRNA levels in seven-month-old C57BL/6J male and female mice treated with DMSO or Oligomycin (0.5 mg/kg, ip).
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Nat Commun
2022 Jun 17;13(1):3486. PMID: 35710796 -
J Am Chem Soc
2023 Oct 18;145(41):22433-22441. PMID: 37812815
Oligomycin purchased from MedChemExpress. Usage Cited in: J Am Chem Soc. 2023 Oct 18;145(41):22433-22441. [Abstract]
Typical curves showing temperature fluctuations of individual cells at different time intervals in the absence of stimulus (black) and after the addition of Oligomycin (blue) (100 μM).
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Cell Death Differ
PDK4-driven lactate accumulation facilitates LPCAT2 lactylation to exacerbate sepsis-induced acute lung injury. [Abstract]2025 Oct 7. PMID: 41057687 -
Autophagy
ATG9A-PLA2G6 axis reprograms phospholipid metabolism to drive metabolic liver disease and hepatocellular carcinoma. [Abstract]2025 Dec 26:1-18. PMID: 41358570 -
Autophagy
Copper aggravated synaptic damage after traumatic brain injury by downregulating BNIP3-mediated mitophagy. [Abstract]2025 Mar;21(3):548-564. PMID: 39415457 -
Autophagy
Signal-sustained imaging of mitophagy with an Enzyme-Activatable Metabolic Lipid-Labeling Probe. [Abstract]2024 Nov;20(11):2556-2570. PMID: 38873937 -
Adv Sci (Weinh)
Faecalibaculum rodentium Alleviates Ionizing Radiation-Induced Damage in Mice by Improving Intestinal Integrity and Hematopoiesis via Its Metabolite Butyrate. [Abstract]2025 Oct 13:e09383. PMID: 41082369 -
Adv Sci (Weinh)
Massage-Mimicking Nanosheets Mechanically Reorganize Inter-organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease. [Abstract]2025 Apr 13:e2413376. PMID: 40223359
Oligomycin purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Apr 13:e2413376. [Abstract]
Fluorescence images of cellular ROS levels: NanoMassage ameliorate ROS generation and cell apoptosis induced by CCCP or Oligomycin (10 μM, 1 h) in neuron-like cells.
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J Adv Res
Parkin modulates the hepatocellular carcinoma microenvironment by regulating PD-1/PD-L1 signalling. [Abstract]2025 Jan 2:S2090-1232(24)00623-4. PMID: 39755271
Oligomycin purchased from MedChemExpress. Usage Cited in: J Adv Res. 2025 Jan 2:S2090-1232(24)00623-4. [Abstract]
Real-time analysis of the OCR was carried out with a Seahorse analyser with single cells from mice liver tissues following treatment with Oligomycin (1.5 μM).
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Biomaterials
Radiation-triggerable bioreactors enable bioenergetic reprograming of cancer stem cell plasticity via targeted arginine metabolism disruption for augmented radio-immunotherapy. [Abstract]2025 May 5:322:123391. PMID: 40344881 -
Exp Mol Med
Simultaneous treatment with sorafenib and glucose restriction inhibits hepatocellular carcinoma in vitro and in vivo by impairing SIAH1-mediated mitophagy. [Abstract]2022 Nov;54(11):2007-2021. PMID: 36385558 -
J Exp Clin Cancer Res
CYP3A5 promotes glioblastoma stemness and chemoresistance through fine-tuning NAD+/NADH ratio. [Abstract]2025 Jan 3;44(1):3. PMID: 39754188 -
J Nanobiotechnology
Radiocleavable rare-earth nanoactivators targeting over-expressed folate receptors induce mitochondrial dysfunction and remodel immune suppressive microenvironment in pancreatic cancer. [Abstract]2025 Aug 12;23(1):562. PMID: 40797208 -
Redox Biol
Redistribution of defective mitochondria-mediated dihydroorotate dehydrogenase imparts 5-fluorouracil resistance in colorectal cancer. [Abstract]2024 May 23:73:103207. PMID: 38805974 -
Redox Biol
Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation. [Abstract]2021 Jul:43:101994. PMID: 33964586 -
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EBioMedicine
Differential regulation of FADS2 by EZH2 reveals a metabolic vulnerability in ovarian cancer treatment. [Abstract]2025 Aug 15:119:105879. PMID: 40818202 -
Pharmacol Res
Novel selective hexokinase 2 inhibitor Benitrobenrazide blocks cancer cells growth by targeting glycolysis. [Abstract]2021 Feb:164:105367. PMID: 33307221 -
Cancer Lett
Obesity accelerates immune evasion of non-small cell lung carcinoma via TFEB-dependent upregulation of Siglec-15 and glycolytic reprogramming. [Abstract]2022 Dec 1:550:215918. PMID: 36150633 -
Cell Death Dis
YBX1 orchestrates LDHA-mediated metabolic reprogramming and NF-κB activation to drive clear cell renal cell carcinoma progression. [Abstract]2026 Jan 8;17(1):11. PMID: 41507134 -
Cell Death Dis
Impaired natural killer cell migration in HIV-infected individuals is caused by TIGIT-mediated inhibition of HIF-1α-dependent glycolysis. [Abstract]2025 Nov 7;16(1):805. PMID: 41203617 -
Cell Death Dis
LncRNA SNHG26 promotes gastric cancer progression and metastasis by inducing c-Myc protein translation and an energy metabolism positive feedback loop. [Abstract]2024 Mar 29;15(3):236. PMID: 38553452 -
Cell Death Dis
The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization. [Abstract]2022 Oct 26;13(10):899. PMID: 36289190 -
Cell Death Dis
Mitochondrial quality control protects photoreceptors against oxidative stress in the H2O2-induced models of retinal degeneration diseases. [Abstract]2021 Apr 20;12(5):413. PMID: 33879768 -
Proc Natl Acad Sci U S A
Endogenous ATP-powered nanomotors directing neural stem cell differentiation for Parkinson's disease treatment. [Abstract]2026 Mar 31;123(13):e2520119123. PMID: 41880568 -
Dev Cell
2025 Apr 18:S1534-5807(25)00206-0. PMID: 40280135 -
Acta Pharmacol Sin
YOD1 mediates isoproterenol-induced cardiac remodeling by deubiquitinating PKM2 and reducing PKM2 tetramerization in cardiomyocytes. [Abstract]2025 Jun 11. PMID: 40500343 -
Phytomedicine
Notopterol attenuates synovitis via α7nAChR-dependent metabolic reprogramming of macrophage polarisation. [Abstract]2025 Dec 9:150:157684. PMID: 41442994 -
EMBO Mol Med
Glycine decarboxylase advances IgA nephropathy by boosting mesangial cell proliferation through the pyrimidine pathway. [Abstract]2025 Oct 13. PMID: 41083822 -
Phytomedicine
Ganoderic acid D attenuates gemcitabine resistance of triple-negative breast cancer cells by inhibiting glycolysis via HIF-1α destabilization. [Abstract]2024 Jul:129:155675. PMID: 38678954 -
ACS Appl Mater Interfaces
Bioactive Light-Responsive Au Nanohybrids for Reactive Oxygen Species-Driven Macrophage Reprogramming. [Abstract]2025 Oct 1;17(39):54453-54465. PMID: 40956059 -
Free Radic Biol Med
Salvianolic acid B drives gluconeogenesis and peroxisomal redox remodeling in cardiac ischemia/reperfusion injury: A metabolism regulation by metabolite signal crosstalk. [Abstract]2025 Mar 1:229:399-414. PMID: 39855316 -
Free Radic Biol Med
2024 Jul 9:S0891-5849(24)00552-5. PMID: 38992393 -
Free Radic Biol Med
BDNF mimetic 7,8-dihydroxyflavone rescues rotenone-induced cytotoxicity in cardiomyocytes by ameliorating mitochondrial dysfunction. [Abstract]2023 Mar:198:83-91. PMID: 36764626 -
Cancer Immunol Res
Herpes virus entry mediator costimulation signaling enhances CAR-T cell efficacy against solid tumors through metabolic reprogramming. [Abstract]2023 Apr 3;11(4):515-529. PMID: 36689620 -
NPJ Precis Oncol
TRIM65 regulates glucose metabolic reprogramming to promote glioma cell proliferation via ubiquitination and degradation of AMPK. [Abstract]2025 Jun 5;9(1):163. PMID: 40473847 -
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J Transl Med
S1PR3 inhibition protects against LPS-induced ARDS by inhibiting NF-κB and improving mitochondrial oxidative phosphorylation. [Abstract]2024 Jun 5;22(1):535. PMID: 38840216 -
J Transl Med
Hypoxia-induced P4HA1 overexpression promotes post-ischemic angiogenesis by enhancing endothelial glycolysis through downregulating FBP1. [Abstract]2024 Jan 18;22(1):74. PMID: 38238754 -
J Transl Med
ESRRG-PKM2 axis reprograms metabolism to suppress esophageal squamous carcinoma progression and enhance anti-PD-1 therapy efficacy. [Abstract]2023 Sep 7;21(1):605. PMID: 37679788 -
J Transl Med
Rutaecarpine induces the differentiation of triple-negative breast cancer cells through inhibiting fumarate hydratase. [Abstract]2023 Aug 18;21(1):553. PMID: 37592347 -
Stem Cell Res Ther
Genome editing of TXNIP in human pluripotent stem cells for the generation of hepatocyte-like cells and insulin-producing islet-like aggregates. [Abstract]2025 May 4;16(1):225. PMID: 40320524 -
Oncogene
The tumor suppressor Parkin exerts anticancer effects through regulating mitochondrial GAPDH activity. [Abstract]2024 Oct;43(44):3215-3226. PMID: 39285229 -
Aging Cell
Dietary Citrate Restores Age-Related Endothelial Cell Mitochondrial Dysfunction and Alleviates Atherosclerosis. [Abstract]2025 Oct;24(10):e70213. PMID: 40905413 -
Cell Death Discov
DNMBP-AS1/hsa-miR-30a-5p/PGC1α axis suppresses tumor progression of colorectal cancer by inhibiting PKM2-mediated Warburg effect and enhance anti-PD-1 therapy efficacy. [Abstract]2025 Jul 2;11(1):299. PMID: 40603870 -
Cell Death Discov
NDUFB7 mutations cause brain neuronal defects, lactic acidosis, and mitochondrial dysfunction in humans and zebrafish. [Abstract]2025 Mar 1;11(1):82. PMID: 40025060 -
Cell Rep
TRIM65 as a key regulator of ferroptosis and glycolysis in lactate-driven renal tubular injury and diabetic kidney disease. [Abstract]2025 Jul 30;44(8):116091. PMID: 40748757 -
Cell Rep
2023 Aug 28;42(9):113044. PMID: 37643085 -
Cell Rep
Resolvin D1 reprograms energy metabolism to promote microglia to phagocytize neutrophils after ischemic stroke. [Abstract]2023 Jun 6;42(6):112617. PMID: 37285269 -
Clin Transl Med
Protein arginine methyltransferase 3 promotes glycolysis and hepatocellular carcinoma growth by enhancing arginine methylation of lactate dehydrogenase A. [Abstract]2022 Jan;12(1):e686. PMID: 35090076 -
Cell Mol Life Sci
m6A reader IGF2BP1 facilitates macrophage glycolytic metabolism and fibrotic phenotype by stabilizing THBS1 mRNA to promote pulmonary fibrosis. [Abstract]2025 Apr 12;82(1):157. PMID: 40220148 -
J Agric Food Chem
Elevated PINK1/Parkin-Dependent Mitophagy and Boosted Mitochondrial Function Mediate Protection of HepG2 Cells from Excess Palmitic Acid by Hesperetin. [Abstract]2024 Jun 12;72(23):13039-13053. PMID: 38809522 -
EMBO Rep
Defective branched-chain amino acid catabolism in dorsal root ganglia contributes to mechanical pain. [Abstract]2023 Nov 6;24(11):e56958. PMID: 37721527 -
Ecotoxicol Environ Saf
Inhibition of mitochondrial calcium uptake by Ru360 enhances the effect of 1800 MHz radio-frequency electromagnetic fields on DNA damage. [Abstract]2023 Oct 1:264:115472. PMID: 37716072 -
Front Immunol
The mTORC1 Signaling Support Cellular Metabolism to Dictate Decidual NK Cells Function in Early Pregnancy. [Abstract]2022 Mar 10;13:771732. PMID: 35359988 -
Mar Drugs
Antiproliferative Activity and Potential Mechanism of Marine-Sourced Streptoglutarimide H against Lung Cancer Cells. [Abstract]2021 Jan 31;19(2):79. PMID: 33572615 -
Cancer Metab
Unveiling the powerhouse: ASCL1-driven small cell lung cancer is characterized by higher numbers of mitochondria and enhanced oxidative phosphorylation. [Abstract]2025 Mar 31;13(1):16. PMID: 40165271 -
Cancer Metab
Tadalafil increases the antitumor activity of 5-FU through inhibiting PRMT5-mediated glycolysis and cell proliferation in colorectal cancer. [Abstract]2022 Dec 6;10(1):22. PMID: 36474242 -
Life Sci
Aberrant interferon-γ signaling disrupts trophoblast invasion via IDO1/AHR signaling and metabolic reprogramming associated with recurrent pregnancy loss. [Abstract]2026 Apr 1:390:124256. PMID: 41655779 -
Int J Mol Sci
The SIRT5-Mediated Upregulation of C/EBPβ Promotes White Adipose Tissue Browning by Enhancing UCP1 Signaling. [Abstract]2024 Sep 29;25(19):10514. PMID: 39408844 -
iScience
Dynamic regulation of P-TEFb by 7SK snRNP is integral to the DNA damage response to regulate chemotherapy sensitivity. [Abstract]2022 Aug 4;25(9):104844. PMID: 36034227 -
iScience
2021 Sep 25;24(10):103170. PMID: 34646996 -
Virol Sin
Thapsigargin suppresses porcine hemagglutinating encephalomyelitis virus replication by disrupting host energy metabolism. [Abstract]2025 Nov 21:S1995-820X(25)00161-0. PMID: 41276220 -
Drug Metab Dispos
Activation of pregnane X receptor-organic anion transporting polypeptide 1a/b /P-glycoprotein/multidrug resistance protein 2 axis mediates the accelerated blood and liver clearance of PEGylated liposomes. [Abstract]2025 Nov;53(11):100172. PMID: 41106060 -
J Virol
p53-mediated regulation of electron transport chain and nucleotide synthesis during Newcastle disease virus infection. [Abstract]2025 Nov 25;99(11):e0157625. PMID: 41170972 -
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Expert Rev Clin Immunol
TFDP1 activates SPC25-mediated glutamine metabolism to repress anti-tumor immunity of NK cells in lung adenocarcinoma. [Abstract]2025 Jun 25:1-11. PMID: 40552366 -
Int Dent J
The Immune Regulatory Mechanism of Adrenomedullin on Promoting the Proliferation and Differentiation of Dental Pulp Stem Cells. [Abstract]2024 May 27:S0020-6539(24)00125-4. PMID: 38806333 -
Toxicol Appl Pharmacol
RUNDC3A-AS1 is an adverse prognostic factor for triple-negative breast cancer which mediates the Warburg effect and Adriamycin resistance by targeting miR-224-3p/COL5A2. [Abstract]2026 Feb 27:511:117776. PMID: 41765289 -
Toxicol Appl Pharmacol
7,8-Dihydroxyflavone attenuates cisplatin-induced cardiomyocyte apoptosis and mitochondrial dysfunction via the p53/Nrf2 pathway. [Abstract]2025 Sep 22:505:117578. PMID: 40992637 -
Toxicol Appl Pharmacol
BDNF mimetics recover palmitic acid-induced injury in cardiomyocytes by ameliorating Akt-dependent mitochondrial impairments. [Abstract]2024 May:486:116951. PMID: 38705401 -
Biochim Biophys Acta Mol Cell Biol Lipids
Cytoskeleton regulates lipid droplet fusion and lipid storage by controlling lipid droplet movement. [Abstract]2025 Apr 4:159610. PMID: 40189192 -
Pathol Res Pract
USP18 improves mitochondrial homeostasis by stabilizing PKM2 and promoting M2 polarization in macrophages to relieve acute lung injury. [Abstract]2026 Apr:280:156383. PMID: 41653510 -
J Bioenerg Biomembr
METTL16-mediated m6A modification of LYRM2 drives breast cancer progression by inducing CD8+ T cell dysfunction via Glycolysis. [Abstract]2026 Mar 18. PMID: 41849076 -
Immunopharmacol Immunotoxicol
Extracellular vesicle-derived LINC00511 promotes glycolysis and mitochondrial oxidative phosphorylation of pancreatic cancer through macrophage polarization by microRNA-193a-3p-dependent regulation of plasminogen activator urokinase. [Abstract]2023 Jun;45(3):355-369. PMID: 36476048 -
J Immunother
HES6 Mediates Oxidative Phosphorylation Pathway to Promote Immune Infiltration of CD8+ T Cells in Lung Adenocarcinoma. [Abstract]2024 Oct 1;47(8):313-322. PMID: 39005046 -
Free Radic Res
2024 Jul 30:1-16. PMID: 39079051 -
Int J Biochem Cell Biol
Inhibition of ERO1A by TCF21 curbs aerobic glycolysis and enhances immune recognition in lung adenocarcinoma. [Abstract]2025 Oct:187:106831. PMID: 40659157 -
Vet Microbiol
2025 Oct:309:110695. PMID: 40897026 -
Brain Res
Mitochondrial fatty acid oxidase CPT1A ameliorates postoperative cognitive dysfunction by regulating astrocyte ferroptosis. [Abstract]2024 Dec 24:149424. PMID: 39725377 -
Prostate
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Toxicon
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Oxid Med Cell Longev
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Solvent & Solubility
Ethanol : 30 mg/mL (Need ultrasonic and warming)
DMSO : 20 mg/mL (Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Korean - KR (420 KB)
- Portuguese - PT (420 KB)
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Handling Instructions (2659 KB)
References
[1]. Zhou W, et al. Membrane plasticity facilitates recognition of the inhibitor oligomycin by the mitochondrial ATP synthase rotor. Biochim Biophys Acta Bioenerg. 2018;1859(9):789-796. [Content Brief]
[2]. SMITH RM, et al. Oligomycin, a new antifungal antibiotic. Antibiot Chemother (Northfield). 1954;4(9):962-970. [Content Brief]
[3]. López de Figueroa P, et al. Autophagy activation and protection from mitochondrial dysfunction in human chondrocytes. Arthritis Rheumatol. 2015;67(4):966-976. [Content Brief]
[4]. Gong Y, et al. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells. Am J Physiol Cell Physiol. 2005;288(5):C1023-C1029. [Content Brief]
[5]. Shchepina LA, et al. Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis. Oncogene. 2002;21(53):8149-8157. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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