2. Others Membrane Transporter/Ion Channel Anti-infection
  3. Oxidative Phosphorylation ATP Synthase Fungal Antibiotic
  4. Oligomycin

Oligomycin, an antifungal antibiotic, is an inhibitor of H+-ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells.

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Oligomycin Chemical Structure

Oligomycin Chemical Structure

CAS No. : 1404-19-9

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Based on 28 publication(s) in Google Scholar

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Oligomycin Related Antibodies

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Description

Oligomycin, an antifungal antibiotic, is an inhibitor of H+-ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells[1][2][3][4].

In Vitro

Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Oligomycin Related Antibodies
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Oligomycin]
Structure Classification
Initial Source

Streptomyces
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 30 mg/mL (Need ultrasonic and warming)

DMSO : 20 mg/mL (Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Purity & Documentation

Purity: ≥99.0%

COA (244 KB) HNMR (483 KB)

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Oligomycin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oligomycin1404-19-9Oxidative PhosphorylationATP SynthaseFungalAntibioticoxidativephosphorylationelectrontransportchainrespiratorycomplex VHIF-1alphaInhibitorinhibitorinhibit

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