Oligomycin C
Based on 1 publication(s) in Google Scholar
Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria.
For research use only. We do not sell to patients.
- Purity: 99.26%
- CAS No.: 11052-72-5
- Formula: C45H74O10
- Molecular Weight:775.06
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Oligomycin C
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Biological Activity
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Macrolide |
Interaction of oligomycin C with purified CYP107W1 results in a type I binding with Kd value of 14.4 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 11052-72-5
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Appearance Solid
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Molecular Weight 775.06
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Formula C45H74O10
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Color White to off-white
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SMILES
O=C([C@@H]([C@H]([C@@H](C([C@H]([C@H]([C@@H](C/C=C/C=C/[C@@]([H])(CC[C@]1([C@H]([C@@]([H])(O2)[C@@H]([C@]3(O1)CC[C@@H]([C@@]([H])(O3)C[C@@H](C)O)C)C)C)[H])CC)C)O)C)=O)C)O)C)[C@H]([C@@H]([C@H](/C=C/C2=O)C)O)C
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Structure Classification
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Initial Source
Streptomyces
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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J Appl Toxicol
The glycolytic shift was involved in CdTe/ZnS quantum dots inducing microglial activation mediated through the mTOR signaling pathway. [Abstract]2020 Mar;40(3):388-402. PMID: 31802521
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Yang PW, et al. Oligomycins A and C, major secondary metabolites isolated from the newly isolated strain Streptomyces diastaticus. Folia Microbiol (Praha). 2010;55(1):10-16. [Content Brief]
[2]. Han S, et al. Functional characterization of CYP107W1 from Streptomyces avermitilis and biosynthesis of macrolide oligomycin A. Arch Biochem Biophys. 2015;575:1-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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