504-88-1
504-88-1
Chemical Structure
3-Nitropropanoic acid
Synonym(s): β-Nitropropionic acid; Bovinocidin
- CAS No.: 504-88-1
- Formula:C3H5NO4
- Molecular Weight:119.08
IUPAC Name: 3-nitropropanoic acid
InChIKey: WBLZUCOIBUDNBV-UHFFFAOYSA-N
SMILES: O=C(O)CC[N+]([O-])=O
Biological Activity: 3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible and orally active inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM. 3-Nitropropanoic acid can induce cell apoptosis[1][2].
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3-Nitropropanoic acid | 99.94% | 3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible and orally active inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM. 3-Nitropropanoic acid can induce cell apoptosis. | ||||||||||||||||||||
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3-Nitropropanoic acid (Standard) | ≥98% | 3-Nitropropanoic acid (Standard) is the analytical standard of 3-Nitropropanoic acid. This product is intended for research and analytical applications. 3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible and orally active inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM. 3-Nitropropanoic acid can induce cell apoptosis. | ||||||||||||||||||||
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References
- [1]. Huang LS, et al. 3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme. J Biol Chem. 2006 Mar 3;281(9):5965-72. [Content Brief]
- [2]. Chomcheon P, et al. 3-Nitropropionic acid (3-NPA), a potent antimycobacterial agent from endophytic fungi: is 3-NPA in some plants produced by endophytes? J Nat Prod. 2005 Jul;68(7):1103-5. [Content Brief]
