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Cat. No.: HY-N0886R

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Aloin B (Standard)

(Synonyms: Isobarbaloin (Standard))

Aloin B (Isobarbaloin) (Standard) is the analytical standard of Aloin B. This product is intended for research and analytical applications. Aloin B is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC₅₀ of 16.08 μM (hydrolytic activity) and 17.51 μM (deubiquitinase activity). Aloin B is metabolized by rat intestinal flora into aloe-emodin-9-anthrone to exert laxative effects. Aloin B inhibits TPA (HY-18739)-induced ear edema, putrescine elevation, and tumor promotion in mouse skin. Aloin B can be used in research related to anti-inflammation, tumor promotion inhibition, coronavirus disease 2019 (COVID-19) and constipation.

For research use only. We do not sell to patients.

CAS No.: 28371-16-6
Formula: C₂₁H₂₂O₉
Molecular Weight:418.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Aloin B (Standard) Chemical Structure

CAS No.: 28371-16-6

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Product Information
- Information
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
Bioz

Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 28371-16-6
Molecular Weight 418.39
Formula C₂₁H₂₂O₉
SMILES

O[C@H]([C@H]1O)[C@](O[C@H](CO)[C@H]1O)([H])[C@@](C2=CC=CC(O)=C23)([H])C(C=C(CO)C=C4O)=C4C3=O
Synonyms

Isobarbaloin (Standard)
Structure Classification
- Quinones
- Anthraquinones
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Fani M, et al. Inhibitory activity of Aloe vera gel on some clinically isolated cariogenic and periodontopathic bacteria. J Oral Sci. 2012 Mar;54(1):15-21. [Content Brief]

[2]. Abd-Alla HI, et al. New bioactive compounds from Aloe hijazensis. Nat Prod Res. 2009;23(11):1035-49. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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