2. Reference Standards
  3. Natural Product Standards
  4. Quinones

Quinones

Quinones represent a class of compounds that are widely distributed in nature. They are found in a wide variety of plants. They are also present in fungi, bacteria and in small amounts in animals. Quinones have a common basic structural pattern: an ortho or a para substituted dione conjugated either to an aromatic nucleus (benzoquinones) or to a condensed polycyclic aromatic system, such as Benzene quinones, Naphthalene quinones, Phenanthrenequinones and Anthraquinones. Quinones have potential biological activities for antioxidant, anti-inflammatory, antibiotic, anti-microbial, and anti-cancer activities. Anthraquinone derivatives, an important subclass of quinones show a wide array of pharmacological activities including laxative, anti-cancer, anti-inflammatory, anti-arthritic, anti-fungal, anti-bacterial, antiviral, anti-platelet aggregation and neuroprotective activity.

Quinones (70):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15142R
    Doxorubicin hydrochloride (Standard) 25316-40-9
    Doxorubicin hydrochloride (Standard) is the analytical standard of Doxorubicin hydrochloride. This product is intended for research and analytical applications. Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy.
    Doxorubicin hydrochloride (Standard)
  • HY-N0111R
    Coenzyme Q10 (Standard) 303-98-0
    Coenzyme Q10 (Standard) is the analytical standard of Coenzyme Q10. This product is intended for research and analytical applications. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
    Coenzyme Q10 (Standard)
  • HY-B0332R
    Menadione (Standard) 58-27-5
    Menadione (Standard) is the analytical standard of Menadione. This product is intended for research and analytical applications. Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer.
    Menadione (Standard)
  • HY-B2156R
    Menaquinone-4 (Standard) 863-61-6
    Menaquinone-4 (Standard) is the analytical standard of Menaquinone-4. This product is intended for research and analytical applications. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.
    Menaquinone-4 (Standard)
  • HY-14393R
    Emodin (Standard) 518-82-1
    Emodin (Standard) is the analytical standard of Emodin. This product is intended for research and analytical applications. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice.
    Emodin (Standard)
  • HY-N0684R
    Vitamin K1 (Standard) 84-80-0
    Vitamin K1 (Standard) is the analytical standard of Vitamin K1. This product is intended for research and analytical applications. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
    Vitamin K1 (Standard)
  • HY-N0189R
    Aloe emodin (Standard) 481-72-1
    Aloe emodin (Standard) is the analytical standard of Aloe emodin. This product is intended for research and analytical applications.
    Aloe emodin (Standard)
  • HY-N0822R
    Shikonin (Standard) 517-89-5
    Shikonin (Standard) is the analytical standard of Shikonin. This product is intended for research and analytical applications. Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM. Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway. Shikonin decreases exosome secretion through the inhibition of glycolysis. Shikonin inhibits AIM2 inflammasome activation.
    Shikonin (Standard)
  • HY-100196R
    Pyrroloquinoline quinone (Standard) 72909-34-3
    Pyrroloquinoline quinone (Standard) is the analytical standard of Pyrroloquinoline quinone. This product is intended for research and analytical applications. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function.
    Pyrroloquinoline quinone (Standard)
  • HY-N0105R
    Rhein (Standard) 478-43-3
    Rhein (Standard) is the analytical standard of Rhein. This product is intended for research and analytical applications.
    Rhein (Standard)
  • HY-N0365R
    Sennoside A (Standard) 81-27-6
    Sennoside A (Standard) is the analytical standard of Sennoside A. This product is intended for research and analytical applications. Sennoside A is an anthraquinone glycoside, found in Senna (Cassia angustifolia). Sennoside A is a HIV-1 inhibitor effective on HIV-1 replication.
    Sennoside A (Standard)
  • HY-N0123R
    Aloin-A (Standard) 1415-73-2
    Aloin (Standard) is the analytical standard of Aloin. This product is intended for research and analytical applications. Aloin (Aloin-A; Barbaloin-A) is a natural anti-tumor anthraquinone glycoside with iron chelating activity. Aloin induces the differentiation of MC3T3-E1 cells into osteoblasts through MAPK-mediated Wnt and Bmp signaling pathways. Alkaline phosphatase (ALP) is an early marker of osteoblast differentiation, and the activity of ALP is also enhanced by Aloin. Aloin also reduces brain edema, reduces blood-brain barrier disruption and improves cortical impact injuries. Aloin is used in research into osteoporosis and traumatic brain injury (TBI).
    Aloin-A (Standard)
  • HY-N0135R
    Tanshinone IIA (Standard) 568-72-9
    Tanshinone IIA (Standard) is the analytical standard of Tanshinone IIA. This product is intended for research and analytical applications. Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.
    Tanshinone IIA (Standard)
  • HY-B0923R
    Danthron (Standard) 117-10-2
    Danthron (Standard) is the analytical standard of Danthron. This product is intended for research and analytical applications. Danthron is a natural product extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge. Danthron functions in regulating glucose and lipid metabolism by activating AMPK.
    Danthron (Standard)
  • HY-101415R
    Coenzyme Q9 (Standard) 303-97-9
    Coenzyme Q9 (Standard) is the analytical standard of Coenzyme Q9. This product is intended for research and analytical applications. Coenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes-induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis.
    Coenzyme Q9 (Standard)
  • HY-15230R
    Geldanamycin (Standard) 30562-34-6
    Geldanamycin (Standard) is the analytical standard of Geldanamycin. This product is intended for research and analytical applications. Geldanamycin is a Hsp90 inhibitor with antimicrobial activity against many Gram-positive and some Gram-negative bacteria. Geldanamycin has anti-influenza virus H5N1 activities.
    Geldanamycin (Standard)
  • HY-N0563R
    Alizarin (Standard) 72-48-0
    Alizarin (Standard) is the analytical standard of Alizarin. This product is intended for research and analytical applications. Alizarin is a natural dye extracted from the roots of madder plant and has been widely used as a pigment in textile fabrics and paintings.
    Alizarin (Standard)
  • HY-N8407R
    Carminic acid (Standard) 1260-17-9
    Carminic acid (Standard) is the analytical standard of Carminic acid (HY-N8407). This product is intended for research and analytical applications. Carminic acid is a widely used and orally active natural red pigment that can be used in industries such as food, cosmetics, and pharmaceuticals. In addition, carminic acid has anti-inflammatory and antioxidant activities.
    Carminic acid (Standard)
  • HY-N7526R
    Naphthazarin (Standard) 475-38-7
    Naphthazarin (DHNQ) is a naturally occurring compound. Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. Naphthazarin triggers apoptosis and has anti-tumor effects.
    Naphthazarin (Standard)
  • HY-121309R
    Doxorubicinone (Standard) 24385-10-2
    Doxorubicinone (Adriamycin aglycone) (Standard) is the analytical standard of Doxorubicinone. This product is intended for research and analytical applications. Doxorubicinone is the aglycone of the antibiotic Doxorubicin (HY-15142A), i.e., its sugar-free parent nucleus structure. Doxorubicinone does not induce DNA damage or bind to RelA, but still downregulates the expression of pro-inflammatory cytokines (such as TNF, IL-12, etc.) regulated by the NF-κB pathway. Doxorubicinone can be used in sepsis-related research.
    Doxorubicinone (Standard)