42017-89-0
42017-89-0
Chemical Structure
Fenofibric acid
Synonym(s): FNF acid
- CAS No.: 42017-89-0
- Formula:C17H15ClO4
- Molecular Weight:318.76
IUPAC Name: 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoic acid
InChIKey: MQOBSOSZFYZQOK-UHFFFAOYSA-N
SMILES: CC(C)(OC1=CC=C(C(C2=CC=C(Cl)C=C2)=O)C=C1)C(O)=O
Biological Activity: Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 μM, 1.47 μM, and 1.06 μM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fenofibric acid | 99.94% | Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 μM, 1.47 μM, and 1.06 μM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM. | ||||||||||||||||||||
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Fenofibric acid (Standard) | 99.57% | Fenofibric acid (Standard) is the analytical standard of Fenofibric acid. This product is intended for research and analytical applications. Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 μM, 1.47 μM, and 1.06 μM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM. | ||||||||||||||||||||
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Fenofibric acid-d4 | Fenofibric acid-d4 (FNF acid-d4) is deuterium labeled Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 μM, 1.47 μM, and 1.06 μM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM. | |||||||||||||||||||||
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Fenofibric acid-d6 | 99.51% | Fenofibric acid-d6 (FNF acid-d6) is the deuterium labeled Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM. | ||||||||||||||||||||
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Fenofibric acid-13C8 | Fenofibric acid-13C8 (FNF acid-13C8) is 13C labeled Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 μM, 1.47 μM, and 1.06 μM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM. | |||||||||||||||||||||
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Fenirofibrate | Fenirofibrate (LF 2151), a metabolite of Fenofibrate (HY-17356), is an orally active fibrate, used in the study of hypertriglyceridemia. | |||||||||||||||||||||
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Fenirofibrate-d6 | Fenirofibrate-d6 is the deuterium labeled Fenirofibrate. | |||||||||||||||||||||
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2-Chloro Fenofibric acid-d6 | 2-Chloro Fenofibric acid-d6 is the deuterium labeled 2-Chloro Fenofibric acid. | |||||||||||||||||||||
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3-Chloro Fenofibric acid-d6 | 3-Chloro Fenofibric acid-d6 is the deuterium labeled 3-Chloro Fenofibric acid. | |||||||||||||||||||||
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Hydroxy Bezafibrate-d6 | Hydroxy Bezafibrate-d6 is the deuterium labeled Hydroxy Bezafibrate. | |||||||||||||||||||||
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Choline fenofibrate | 99.54% | Choline Fenofibrate (ABT-335), a choline salt of Fenofibric acid (HY-B0760), releases free Fenofibric acid in the gastrointestinal tract. Fenofibric acid is a PPAR activator with antihyperlipidemic effect. | ||||||||||||||||||||
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Fenofibrate (GMP) | Fenofibrate (GMP) is Fenofibrate (HY-17356) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Fenofibrate is a selective PPARα agonist with an EC50 of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC50s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for CYP2C19, CYP2B6, CYP2C9, CYP2C8, and CYP3A4, respectively. | |||||||||||||||||||||
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Fenofibrate-d6 | 99.70% | Fenofibrate-d6 is the deuterium labeled Fenofibrate. Fenofibrate is a selective PPARα agonist with an EC50 of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC50s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for CYP2C19, CYP2B6, CYP2C9, CYP2C8, and CYP3A4, respectively. | ||||||||||||||||||||
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Fenofibrate-13C6 | Fenofibrate-13C6 is a deuterated labeled Fenofibrate. Fenofibrate is a selective PPARα agonist with an EC50 of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC50s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for CYP2C19, CYP2B6, CYP2C9, CYP2C8, and CYP3A4, respectively. | |||||||||||||||||||||
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Bezafibrate-d6 | 98.0% | Bezafibrate-d6 is the deuterium labeled Bezafibrate. Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic agent. | ||||||||||||||||||||
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Fenirofibrate impurity 6 | Fenirofibrate impurity 6 (Fenirofibrate impurity D) is an impurity of Fenirofibrate. | |||||||||||||||||||||
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Fenirofibrate impurity 8 | Fenirofibrate impurity 8 (Fenirofibrate impurity F) is an impurity of Fenirofibrate. | |||||||||||||||||||||
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Fenirofibrate impurity 1 | Fenirofibrate impurity 1 is an impurity of Fenirofibrate. | |||||||||||||||||||||
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Fenirofibrate impurity 5 | Fenirofibrate impurity 5 is an impurity of Fenirofibrate. | |||||||||||||||||||||
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Fenirofibrate impurity 7 | Fenirofibrate impurity 7 is an impurity of Fenirofibrate. | |||||||||||||||||||||
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