743438-45-1
743438-45-1
Chemical Structure
Chiglitazar
Synonym(s): Carfloglitazar
- CAS No.: 743438-45-1
- Formula:C36H29FN2O4
- Molecular Weight:572.62
IUPAC Name: (S)-3-(4-(2-(9H-carbazol-9-yl)ethoxy)phenyl)-2-((2-(4-fluorobenzoyl)phenyl)amino)propanoic acid
InChIKey: QNLWMPLUWMWDMQ-YTTGMZPUSA-N
SMILES: O=C(C1=CC=C(F)C=C1)C(C=CC=C2)=C2N[C@H](C(O)=O)CC(C=C3)=CC=C3OCCN4C5=CC=CC=C5C6=CC=CC=C46
Biological Activity: Chiglitazar (Carfloglitazar) is a PPARα/γ dual agonist, with EC50s of 1.2, 0.08, 1.7 μM for PPARα, PPARγ and PPARδ, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Chiglitazar | 99.70% | Chiglitazar (Carfloglitazar) is a PPARα/γ dual agonist, with EC50s of 1.2, 0.08, 1.7 μM for PPARα, PPARγ and PPARδ, respectively. | ||||||||||||||||||||
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Chiglitazar (Standard) | ≥98% | Chiglitazar (Standard) is the analytical standard of Chiglitazar (HY-106266). This product is intended for research and analytical applications. Chiglitazar (Carfloglitazar) is a PPARα/γ dual agonist, with EC50s of 1.2, 0.08, 1.7 μM for PPARα, PPARγ and PPARδ, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.93
HY-106266BChiglitazar sodium -
Similarity Score 0.65
HY-15655GW1929 -
Similarity Score 0.65
HY-110022GW1929 hydrochloride -
Similarity Score 0.56
HY-175513ZWZH-21 -
Similarity Score 0.49
HY-119197PPARα/γ/δ agonist 1 -
Similarity Score 0.49
HY-113628AABT-080 free base -
Similarity Score 0.47
HY-12746DC-05 -
Similarity Score 0.47
HY-118941BAY 73-1449 -
Similarity Score 0.47
HY-144430Bcl-2/Mcl-1-IN-1 -
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