PPARα/γ/δ agonist 1
PPARα/γ/δ agonist 1 (Compound 2) is a potent PPARα/γ/δ agonist, with an IC50 of 70 nM for PPARγ. PPARα/γ/δ agonist 1 can be used for the research of type 2 diabetes.
For research use only. We do not sell to patients.
- CAS No.: 853652-40-1
- Formula: C33H31NO5
- Molecular Weight:521.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | EC50 |
0.008 μM
Compound: 10k
|
Effect on PPAR alpha transactivation activity in Huh7 cells
Effect on PPAR alpha transactivation activity in Huh7 cells
|
[PMID: 16451087] |
| Huh-7 | EC50 |
0.008 μM
Compound: 2
|
Activity at human PPAR alpha in Huh7 cells by transactivation assay
Activity at human PPAR alpha in Huh7 cells by transactivation assay
|
[PMID: 17034149] |
| Huh-7 | EC50 |
0.07 μM
Compound: 10k
|
Effect on PPAR gamma transactivation activity in Huh7 cells
Effect on PPAR gamma transactivation activity in Huh7 cells
|
[PMID: 16451087] |
| Huh-7 | EC50 |
0.07 μM
Compound: 2
|
Activity at human PPAR gamma in Huh7 cells by transactivation assay
Activity at human PPAR gamma in Huh7 cells by transactivation assay
|
[PMID: 17034149] |
| Huh-7 | EC50 |
0.5 μM
Compound: 10k
|
Effect on PPAR delta transactivation activity in Huh7 cells
Effect on PPAR delta transactivation activity in Huh7 cells
|
[PMID: 16451087] |
| Huh-7 | EC50 |
0.5 μM
Compound: 2
|
Activity at human PPAR delta in Huh7 cells by transactivation assay
Activity at human PPAR delta in Huh7 cells by transactivation assay
|
[PMID: 17034149] |
Chemical Information
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CAS No. 853652-40-1
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Molecular Weight 521.60
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Formula C33H31NO5
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SMILES
O=C(CN1C=CC2=C1C=CC(OCCCOC3=C(CCC)C4=CC=C(C(C5=CC=CC=C5)=O)C=C4C=C3)=C2)O
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)