Pparδ agonist 5
Pparδ agonist 5, an orally active PPARδ-selective agonist (EC50=0.335 μM), is much greater than that of the prototypical standard GW0742. Pparδ agonist 5 promotes improvements in bone density and microarchitecture in vivo.
For research use only. We do not sell to patients.
- Formula: C23H21F3N2O2S
- Molecular Weight:446.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PPARδ 0.335 μM (EC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57BL/6 female mice[1]
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Dosage:10 mg per kg of body weight
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Administration:P.o.; per day for 6 weeks
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Result:Improved the bone density at least back to normal (sham control) levels.
Chemical Information
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Molecular Weight 446.49
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Formula C23H21F3N2O2S
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SMILES
OC(/C=C/C1=CC=C(N(C)CC2=C(C)N=C(C3=CC=C(C(F)(F)F)C=C3)S2)C=C1C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)