1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
    Vitamin D Related/Nuclear Receptor
  3. PPAR
  4. PPARδ Isoform
  5. PPARδ Antagonist

PPARδ Antagonist

PPARδ Antagonist (1):

Cat. No. Product Name Effect Purity
  • HY-182619
    PPARα/δ antagonist-1
    Antagonist
    PPARα/δ antagonist-1 is an orally active, highly selective dual antagonist of PPARα, with IC50 values of 0.113 μM and 0.025 μM against human PPARα and PPARδ, respectively. PPARα/δ antagonist-1 exhibits an excellent in vitro activity profile and preliminary efficacy in mouse tumor models. PPARα/δ antagonist-1 can be used in studies related to cancers (melanoma metastasis, ovarian cancer).