15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester
15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivate of 15-Deoxy-Δ-12,14-prostaglandin J2 (HY-108568). 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 µM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM.
For research use only. We do not sell to patients.
- CAS No.: 1947405-90-4
- Formula: C23H34O5
- Molecular Weight:390.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
PPARγ 2 μM (EC50) |
PPARδ |
Chemical Information
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CAS No. 1947405-90-4
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Molecular Weight 390.51
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Formula C23H34O5
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SMILES
CCCCC/C=C/C=C1[C@H](C=CC\1=O)C/C=C\CCCC(OC(CO)CO)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)