PPARα/δ agonist 3
PPARα/δ agonist 3 (Compound 8) is the orally active agonist for PPAR, that activates PPARα, PPARδ and PPARγ with EC50s of 5.6, 3.4 and 1278 nM, respectively. PPARα/δ agonist 3 exhibits anticholestatic activity in mouse ANIT- or CDCA (HY-76847)-induced cholestatic liver disease models.
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- CAS No.: 3050611-33-8
- Formula: C23H25F3N2O4
- Molecular Weight:450.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PPARδ 3.4 nM (IC50) |
PPARα 5.6 nM (IC50) |
PPARγ 1278 nM (IC50) |
Chemical Information
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CAS No. 3050611-33-8
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Molecular Weight 450.45
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Formula C23H25F3N2O4
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SMILES
CC(C)(OC1=C(C)C=C(CN2CCN(C3=CC=C(C(F)(F)F)C=C3)C2=O)C=C1C)C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PPARα/δ agonist 3 Related Classifications
HY-168485 Related Classifications
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