10465-81-3
Chemical Structure
1,1'-(Azodicarbonyl)-dipiperidine
Synonym(s): ADDP; SR 4077
- CAS No.: 10465-81-3
- Formula:C12H20N4O2
- Molecular Weight:252.31
IUPAC Name: (E)-diazene-1,2-diylbis(piperidin-1-ylmethanone)
InChIKey: OQJBFFCUFALWQL-BUHFOSPRSA-N
SMILES: O=C(/N=N/C(N1CCCCC1)=O)N2CCCCC2
Biological Activity: 1,1'-(Azodicarbonyl)-dipiperidine (ADDP) can be used in the condensation reaction of alcohols with acidic compounds. 1,1'-(Azodicarbonyl)-dipiperidine can also be used in the synthesis of GPR120 agonists with antidiabetic activity, as well as the synthesis of triple agonists for PPARα, PPARγ, and PPARδ. 1,1'-(Azodicarbonyl)-dipiperidine can be used in metabolic disease research[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1,1'-(Azodicarbonyl)-dipiperidine | 97.0% | 1,1'-(Azodicarbonyl)-dipiperidine (ADDP) can be used in the condensation reaction of alcohols with acidic compounds. 1,1'-(Azodicarbonyl)-dipiperidine can also be used in the synthesis of GPR120 agonists with antidiabetic activity, as well as the synthesis of triple agonists for PPARα, PPARγ, and PPARδ. 1,1'-(Azodicarbonyl)-dipiperidine can be used in metabolic disease research. | ||||||||||||||||||||
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References
- [1]. Tsunoda T, et al. 1, 1′-(azodicarbonyl) dipiperidine-tributylphosphine, a new reagent system for mitsunobu reaction[J]. Tetrahedron letters, 1993, 34(10): 1639-1642.
- [2]. Hirose D, et al. Systematic Evaluation of 2-Arylazocarboxylates and 2-Arylazocarboxamides as Mitsunobu Reagents. J Org Chem. 2018 Apr 20;83(8):4712-4729. [Content Brief]
- [3]. Zhang X, et al. Design, synthesis and SAR of a novel series of heterocyclic phenylpropanoic acids as GPR120 agonists. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3272-3278. [Content Brief]
- [4]. Mogensen JP, et al. Design and synthesis of novel PPARalpha/gamma/delta triple activators using a known PPARalpha/gamma dual activator as structural template. Bioorg Med Chem Lett. 2003 Jan 20;13(2):257-60. [Content Brief]
