sEH-IN-26
sEH-IN-26 is a urea structure-based soluble epoxide hydrolase (sEH) inhibitor with selectivity for mammalian cytosolic and peroxisomal sEH. sEH-IN-26 can be used for the research of inflammation and epoxide hydrolase-related diseases.
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- CAS No.: 2222-58-4
- Formule: C14H26N2O
- Masse moléculaire:238.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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sEH |
sEH-IN-26 (compound 57) potently inhibits soluble epoxide hydrolase, with an IC50 of 0.06 μM against mouse sEH and 0.16 μM against human sEH. It shows almost no inhibitory effect on rat microsomal mEH, with an IC50 greater than 500 μM, and exhibits extremely high subtype selectivity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2222-58-4
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Masse moléculaire 238.37
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Formule C14H26N2O
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SMILES
O=C(NC1CCCCC1)NCC2CCCCC2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)