sEH-IN-26
sEH-IN-26 is a urea structure-based soluble epoxide hydrolase (sEH) inhibitor with selectivity for mammalian cytosolic and peroxisomal sEH. sEH-IN-26 can be used for the research of inflammation and epoxide hydrolase-related diseases.
For research use only. We do not sell to patients.
- CAS No.: 2222-58-4
- Formula: C14H26N2O
- Molecular Weight:238.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
sEH |
In Vitro
sEH-IN-26 (compound 57) potently inhibits soluble epoxide hydrolase, with an IC50 of 0.06 μM against mouse sEH and 0.16 μM against human sEH. It shows almost no inhibitory effect on rat microsomal mEH, with an IC50 greater than 500 μM, and exhibits extremely high subtype selectivity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2222-58-4
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Molecular Weight 238.37
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Formula C14H26N2O
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SMILES
O=C(NC1CCCCC1)NCC2CCCCC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
sEH-IN-26 Related Classifications
HY-187133 Related Classifications
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