2. Signaling Pathways
  3. Cell Cycle/DNA Damage
    Vitamin D Related/Nuclear Receptor
  4. PPAR
  5. PPARα Isoform
  6. PPARα Activator

PPARα Activator

PPARα Activators (11):

Cat. No. Product Name Effect Purity
  • HY-13956
    Pioglitazone
    		Activator 99.66%
    Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
  • HY-N0014
    Icariin
    		Activator 99.06%
    Icariin is a flavonol glycoside.
  • HY-N0019
    Daidzein
    		Activator 99.72%
    Daidzein is a soy isoflavone, which acts as a PPAR activator.
  • HY-15725
    CDDO-Im
    		Activator 98.19%
    CDDO-Im (RTA-403) is an activator of Nrf2 and PPAR, with Kis of 232 and 344 nM for PPARα and PPARγ.
  • HY-B0258
    Gemfibrozil
    		Activator 99.91%
    Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering drug; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively.
  • HY-N2341
    Palmitelaidic Acid
    		Activator ≥99.0%
    Palmitelaidic Acid (9-trans-Hexadecenoic acid) is the trans isomer of palmitoleic acid.
  • HY-N0515
    Ophiopogonin D
    		Activator 98.59%
    Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside.
  • HY-N1990
    Gypenoside XLIX
    		Activator 99.35%
    Gypenoside XLIX, a dammarane-type glycoside, is a prominent component of G.
  • HY-N2118
    Bilobetin
    		Activator 98.30%
    Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin.
  • HY-121538
    CUDA
    		Activator ≥98.0%
    CUDA is a potent inhibitor of soluble epoxide hydrolase (sEH), with IC50s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.
  • HY-N5097
    13-Oxo-9E,11E-octadecadienoic acid
    		Activator
    13-Oxo-9E,11E-octadecadienoic acid, an isomer of 9-oxo-ODA, is a potent PPARα activator derived from tomato juice.