1180-95-6
1180-95-6
Chemical Structure
Taurodeoxycholate sodium
- CAS No.: 1180-95-6
- Formula:C26H44NNaO6S
- Molecular Weight:521.69
IUPAC Name: sodium 2-((R)-4-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonate
InChIKey: YXHRQQJFKOHLAP-FVCKGWAHSA-M
SMILES: C[C@H](CCC(NCCS(=O)(O[Na])=O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C
Biological Activity: Taurodeoxycholate sodium salt is a bile salt-related anionic detergent. Taurodeoxycholate sodium salt is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate sodium salt is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) exhibits anti-inflammatory and neuroprotective effects[1][2][3][9][10].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Taurodeoxycholate sodium | 99.91% | Taurodeoxycholate sodium salt is a bile salt-related anionic detergent. Taurodeoxycholate sodium salt is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate sodium salt is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) exhibits anti-inflammatory and neuroprotective effects. | ||||||||||||||||||||
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Taurodeoxycholate sodium salt (Standard) | 99.89% | Taurodeoxycholate sodium salt (Standard) is a bile salt (Standard)-related anionic detergent. Taurodeoxycholate sodium salt (Standard) is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate sodium salt (Standard) is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) exhibits anti-inflammatory and neuroprotective effects. | ||||||||||||||||||||
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Taurodeoxycholic acid-d4-1 sodium | 99.9% | Taurodeoxycholic acid-d4 (Taurodeoxycholate-d4-1) sodium is the deuterium labeled Taurodeoxycholic acid sodium. Taurodeoxycholate sodium salt is a bile salt-related anionic detergent. Taurodeoxycholic acid is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholic acid is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholic acid (TDCA) exhibits anti-inflammatory and neuroprotective effects. | ||||||||||||||||||||
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Taurodeoxycholate-d6 sodium | 99.4% | Taurodeoxycholate-d6 sodium salt is a bile salt-related anionic detergent. Taurodeoxycholate-d6 sodium salt is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate-d6 sodium salt is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate-d6 (TDCA) exhibits anti-inflammatory and neuroprotective effects. | ||||||||||||||||||||
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Taurodeoxycholat-d4 sodium | Taurodeoxycholat-d4 sodium is the deuterium labeled Taurodeoxycholate sodium (HY-128853). Taurodeoxycholate sodium salt is a bile salt-related anionic detergent. Taurodeoxycholate sodium salt is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate sodium salt is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) exhibits anti-inflammatory and neuroprotective effects. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.99
HY-B1899ARTaurodeoxycholic acid sodium hydrate (Standard) -
Similarity Score 0.91
HY-B1899RTaurodeoxycholic acid (Standard) -
Similarity Score 0.87
HY-201296ATauroursocholic acid sodium -
Similarity Score 0.87
HY-N0545Taurocholic acid sodium -
Similarity Score 0.87
HY-N0545STaurocholic acid-13C2,15N sodium -
Similarity Score 0.87
HY-N15880Tauroallocholic acid sodium -
Similarity Score 0.86
HY-B1131RTaurocholic acid sodium salt hydrate (Standard) -
Similarity Score 0.86
HY-N18949A3α,12α-Dihydroxy-7-oxocholanoyltaurine sodium -
Similarity Score 0.86
HY-113308ATaurolithocholic acid sodium salt -
Explore the MedChemAI to find more analogs
References
- [1]. Villavicencio-Queijeiro A, et al. The fully-active and structurally-stable form of the mitochondrial ATP synthase of Polytomella sp. is dimeric. J Bioenerg Biomembr. 2009 Feb;41(1):1-13. [Content Brief]
- [2]. Kispal G, et al. Isolation and characterization of 3-hydroxyacyl coenzyme A dehydrogenase-binding protein from pig heart inner mitochondrial membrane. J Biol Chem. 1986 Oct 25;261(30):14209-13. [Content Brief]
- [3]. Choi HJ, et al. Evaluation of acute and subacute toxicity of sodium taurodeoxycholate in rats. Drug Chem Toxicol. 2021 May;44(3):268-276. [Content Brief]
- [9]. Zou Y, et al. Taurodeoxycholate ameliorates DSS-induced colitis in mice. Int Immunopharmacol. 2023 Sep;122:110628. [Content Brief]
- [10]. Keene CD, et al. A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease. Exp Neurol. 2001 Oct;171(2):351-60. [Content Brief]
