Taurine (Synonyms: 2-Aminoethanesulfonic acid)

Name: Taurine
Brand: MedChemExpress
SKU: HY-B0351
Rating: 5.0 (17 reviews)

Cat. No.: HY-B0351 Purity: 99.88%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes.

For research use only. We do not sell to patients.

CAS No. : 107-35-7

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	In-stock	Estimated Time of Arrival: December 31
Solid
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
500 g	In-stock	Estimated Time of Arrival: December 31
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Customer Review

Based on 17 publication(s) in Google Scholar

Other Forms of Taurine:

17 Publications Citing Use of MCE Taurine

Cell Proliferation/Viability Assay

In Vivo Efficacy Study

: Taurine purchased from MedChemExpress. Usage Cited in: EMBO J. 2025 Nov 20. [Abstract]; LDH release from NLRP6-WT^tg HIEC-6 cells induced or not with 1 μg/ml doxycycline overnight and infected with WT or Δhly L. monocytogenes EGD for 8 h or treated with 70 mM Taurine.

: Taurine purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Apr 3:S0891-5849(25)00207-2. [Abstract]; CCK-8 assay assessing PC12 cell viability after Taurine (TA, 40-120 mM; 24-72 h) treatment at various concentrations for 24 h (A), 48 h (B), and 72 h (C).

: Taurine purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2022 Nov 20;193(Pt 2):795-807. [Abstract]; Taurine (400 mg/kg; i.p. 30 min before and 12 h after SAH). Bar graphs showed mortality rates at 24 h after subarachnoid hemorrhage (SAH) in mice.

: Taurine purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2022 Nov 20;193(Pt 2):795-807. [Abstract]; Taurine (400 mg/kg; i.p. 30 min before and 12 h after SAH). Western blotting images and quantitative data of relative expression level of ZO-1 and occludin in cerebral cortex at 24 h after subarachnoid hemorrhage (SAH) (n = 4/group).

: Taurine purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2022 Nov 20;193(Pt 2):795-807. [Abstract]; The viability of HT22 treated by different concentration of Taurine (5-20 mM) for 24 h was tested by CCK-8 assay in vitro (n = 6/group).

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Human Endogenous Metabolite

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	10 μM Compound: 1123	Substrate uptake by the Taurine Transporter (TauT, SLC6A6) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC6A6 cells (PubChem AID: 1794824) Substrate uptake by the Taurine Transporter (TauT, SLC6A6) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC6A6 cells (PubChem AID: 1794824)	10.5281/zenodo.7360560
L6	IC₅₀	> 90 μg/mL Compound: 6	Cytotoxicity against rat L6 cells after 72 hrs Cytotoxicity against rat L6 cells after 72 hrs	[PMID: 17765547]

In Vitro

Taurine is one of the most abundant amino acids in the brain and spinal cord, leukocytes, heart and muscle cells, the retina, and indeed almost every tissue throughout the body^[1].
Taurine exhibits diverse biological actions, including protection against ischemia-reperfusion injury, modulation of intracellular calcium concentration, and antioxidant, antiatherogenic and blood pressure-lowering effects^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

125.15

Formula

C₂H₇NO₃S

CAS No.

107-35-7

Appearance

Solid

Color

White to off-white

SMILES

NCCS(=O)(O)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

H₂O : 25 mg/mL (199.76 mM; Need ultrasonic)

DMSO : 1 mg/mL (7.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.9904 mL	39.9521 mL	79.9041 mL
5 mM	1.5981 mL	7.9904 mL	15.9808 mL
10 mM	0.7990 mL	3.9952 mL	7.9904 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 12.5 mg/mL (99.88 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.88%

Select Batch:

Data Sheet (272 KB) SDS (396 KB)

COA (246 KB) HNMR (107 KB) RP-HPLC (241 KB)

Handling Instructions (2659 KB)

References

[1]. Ripps H, Shen W. Review: taurine: a "very essential" amino acid. Mol Vis. 2012;18:2673-2686. [Content Brief]

[2]. Xu YJ, et al. The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 2008;13(2):57-65. [Content Brief]

[3]. Kaneko H, et al. Taurine is an amino acid with the ability to activate autophagy in adipocytes. Amino Acids. 2018;50(5):527-535. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	7.9904 mL	39.9521 mL	79.9041 mL	199.7603 mL
DMSO / H₂O	5 mM	1.5981 mL	7.9904 mL	15.9808 mL	39.9521 mL
H₂O	10 mM	0.7990 mL	3.9952 mL	7.9904 mL	19.9760 mL
	15 mM	0.5327 mL	2.6635 mL	5.3269 mL	13.3174 mL
	20 mM	0.3995 mL	1.9976 mL	3.9952 mL	9.9880 mL
	25 mM	0.3196 mL	1.5981 mL	3.1962 mL	7.9904 mL
	30 mM	0.2663 mL	1.3317 mL	2.6635 mL	6.6587 mL
	40 mM	0.1998 mL	0.9988 mL	1.9976 mL	4.9940 mL
	50 mM	0.1598 mL	0.7990 mL	1.5981 mL	3.9952 mL
	60 mM	0.1332 mL	0.6659 mL	1.3317 mL	3.3293 mL
	80 mM	0.0999 mL	0.4994 mL	0.9988 mL	2.4970 mL
	100 mM	0.0799 mL	0.3995 mL	0.7990 mL	1.9976 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Taurine Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Taurine107-35-72-Aminoethanesulfonic acidAutophagyEndogenous Metaboliteantioxidantantiatherogenicbloodpressure-loweringcardiovascularbilesaltsInhibitorinhibitorinhibit

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Taurine (Synonyms: 2-Aminoethanesulfonic acid)

Customer Review

Other Forms of Taurine:

Taurine Related Antibodies

17 Publications Citing Use of MCE Taurine

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Endogenous Metabolite Isoform Specific Products:

Biological Activity

Purity & Documentation

References

Customer Review

Taurine Related Antibodies

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

Taurine Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

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SAFETY DATA SHEET (SDS)

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