Taurine-13C2
Based on 1 Customer Validation
Taurine-13C2 is the 13C-labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.91%
- No. CAS: 70155-54-3
- Fòrmula: 13C2H7NO3S
- Peso molecular:127.13
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Descripciòn
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Aplicación
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 70155-54-3
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Unlabeled CAS 107-35-7
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Appearance Solid
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Peso molecular 127.13
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Fòrmula 13C2H7NO3S
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Color White to off-white
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SMILES
N[13CH2][13CH2]S(=O)(O)=O
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Synonyms
2-Aminoethanesulfonic acid-13C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
H2O : 25 mg/mL (196.65 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Ripps H, Shen W. Review: taurine: a "very essential" amino acid. Mol Vis. 2012;18:2673-2686. [Content Brief]
[3]. Xu YJ, et al. The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 2008;13(2):57-65. [Content Brief]
[4]. Kaneko H, et al. Taurine is an amino acid with the ability to activate autophagy in adipocytes. Amino Acids. 2018;50(5):527-535. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.8660 mL | 39.3298 mL | 78.6596 mL | 196.6491 mL |
| 5 mM | 1.5732 mL | 7.8660 mL | 15.7319 mL | 39.3298 mL | |
| 10 mM | 0.7866 mL | 3.9330 mL | 7.8660 mL | 19.6649 mL | |
| 15 mM | 0.5244 mL | 2.6220 mL | 5.2440 mL | 13.1099 mL | |
| 20 mM | 0.3933 mL | 1.9665 mL | 3.9330 mL | 9.8325 mL | |
| 25 mM | 0.3146 mL | 1.5732 mL | 3.1464 mL | 7.8660 mL | |
| 30 mM | 0.2622 mL | 1.3110 mL | 2.6220 mL | 6.5550 mL | |
| 40 mM | 0.1966 mL | 0.9832 mL | 1.9665 mL | 4.9162 mL | |
| 50 mM | 0.1573 mL | 0.7866 mL | 1.5732 mL | 3.9330 mL | |
| 60 mM | 0.1311 mL | 0.6555 mL | 1.3110 mL | 3.2775 mL | |
| 80 mM | 0.0983 mL | 0.4916 mL | 0.9832 mL | 2.4581 mL | |
| 100 mM | 0.0787 mL | 0.3933 mL | 0.7866 mL | 1.9665 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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