1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-Carnitine

L-Carnitine  (Synonyms: (R)-Carnitine; Levocarnitine)

Cat. No.: HY-B0399 Purity: ≥98.0%
COA Handling Instructions

L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism.

For research use only. We do not sell to patients.

L-Carnitine Chemical Structure

L-Carnitine Chemical Structure

CAS No. : 541-15-1

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Customer Review

Based on 8 publication(s) in Google Scholar

Other Forms of L-Carnitine:

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Description

L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

L-Carnitine ((R)-Carnitine) (125, 250 mg/kg; i.p.) has a more pronounced bronchodilator effect in this chronic murine asthma model, and decreases urinary LTE4 excretion[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

161.20

Formula

C7H15NO3

CAS No.
SMILES

C[N+](C)(C)C[[email protected]](O)CC([O-])=O

Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (310.17 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.2035 mL 31.0174 mL 62.0347 mL
5 mM 1.2407 mL 6.2035 mL 12.4069 mL
10 mM 0.6203 mL 3.1017 mL 6.2035 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (620.35 mM); Clear solution; Need ultrasonic

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: ≥98.0%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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This equation is commonly abbreviated as: C1V1 = C2V2

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L-Carnitine
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