1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-Carnitine

L-Carnitine (Synonyms: Levocarnitine)

Cat. No.: HY-B0399 Purity: ≥98.0%
Handling Instructions

L-Carnitine (Levocarnitine) is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism.

For research use only. We do not sell to patients.

L-Carnitine Chemical Structure

L-Carnitine Chemical Structure

CAS No. : 541-15-1

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Based on 4 publication(s) in Google Scholar

Other Forms of L-Carnitine:

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Description

L-Carnitine (Levocarnitine) is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

L-carnitine increases β oxidation and the resultant acetyl-coA joins the Krebs's cycle resulting in burning of fats and increases energy production, hence it increases the utilization of cellular fatty acids, and removal of abnormal fat on cellular membrane. It also acts as a fat burner by optimizing fat oxidation and consequently reducing its availability for storage[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

L-carnitine reduces HFD induced lipid perioxidation and alteration of antioxidant biomarker in rats hepatic tissue[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

161.20

Formula

C₇H₁₅NO₃

CAS No.

541-15-1

SMILES

C[N+](C)(C)C[[email protected]](O)CC([O-])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (310.17 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.2035 mL 31.0174 mL 62.0347 mL
5 mM 1.2407 mL 6.2035 mL 12.4069 mL
10 mM 0.6203 mL 3.1017 mL 6.2035 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

L-CarnitineLevocarnitineEndogenous MetaboliteendogenousfattyacidmetabolismmitochondriametabolicimbalanceInhibitorinhibitorinhibit

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L-Carnitine
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