L-Carnitine tartrate
Based on 22 publication(s) in Google Scholar
L-Carnitine tartrate is a highly polar, small zwitterion. L-Carnitine tartrate is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine tartrate functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine tartrate is an antioxidant. L-Carnitine tartrate can ameliorate metabolic imbalances in many inborn errors of metabolism[3].
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 36687-82-8
- Formula: C18H36N2O12
- Molecular Weight:472.48
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) L-Carnitine tartrate
More- Nature. 2025 Jul;643(8070):192-200. [Abstract]
- Cell. 2025 Jan 23;188(2):412-429.e27. [Abstract]
- Cell Metab. 2019 Jul 2;30(1):157-173.e7 [Abstract]
- Autophagy. 2025 Oct 25. [Abstract]
- Nat Commun. 2025 Jul 21;16(1):6695. [Abstract]
- Nat Commun. 2025 Aug 23;16(1):7864. [Abstract]
- Nat Commun. 2022 Jun 17;13(1):3486. [Abstract]
- J Exp Clin Cancer Res. 2025 Nov 24;45(1):1. [Abstract]
- Engineering. 2024 Sep 6.
- Int J Biol Sci. 2025 Jan 1;21(2):725-744. [Abstract]
- Free Radic Biol Med. 2024 Mar:213:174-189. [Abstract]
- Cell Rep. 2026 May 22;45(6):117427. [Abstract]
- Cell Rep. 2024 Aug 7;43(8):114591. [Abstract]
- Biosci Rep. 2021 May 28;41(6):BSR20204250. [Abstract]
- Food Sci Biotechnol. 2024 Feb 12;33(11):2585-2596. [Abstract]
- Nutr Metab. 2021 Jun 24;18(1):65. [Abstract]
- J Anim Sci. 2022 Apr 1;100(4):skac069. [Abstract]
- Vet Microbiol. 2026 May:316:110992. [Abstract]
- J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Jun 25:1243:124210. [Abstract]
- Research Square Preprint. 2021 Jan.
- Biomed Pharmacother. 2020 Sep;129:110506. [Abstract]
- Environ Sci Pollut Res Int. 2018 Feb;25(4):3765-3774. [Abstract]
All Endogenous Metabolite Isoforms
More
Biological Activity
L-Carnitine tartrate reduces superoxide production and HIF1α expression, reduces neuronal apoptosis in rats hippocampal tissue. L-Carnitine tartrate maintain the viability of hippocampal synapses within 48 hours after hypoxia/reoxygenation[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 36687-82-8
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Appearance Solid
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Molecular Weight 472.48
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Formula C18H36N2O12
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Color White to off-white
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SMILES
C[N+](C)(C)C[C@@H](CC(=O)[O-])O.C[N+](C)(C)C[C@@H](CC(=O)[O-])O.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (22)
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Journal Impact Factor
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Most Recent
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Nature
2025 Jul;643(8070):192-200. PMID: 39695227 -
Cell
2025 Jan 23;188(2):412-429.e27. PMID: 39591965 -
Cell Metab
2019 Jul 2;30(1):157-173.e7 PMID: 31155494 -
Autophagy
XIAP-ULK1-Mediated mitophagy modulates carnitine metabolism to mitigate diabetic kidney disease. [Abstract]2025 Oct 25. PMID: 41139215 -
Nat Commun
A UFD1 variant encoding a microprotein modulates UFD1f and IPMK ubiquitination to play pivotal roles in anti-stress responses. [Abstract]2025 Jul 21;16(1):6695. PMID: 40691175 -
Nat Commun
The TEX44-CPT1B axis regulates mitochondrial sheath assembly and fatty acid oxidation in sperm. [Abstract]2025 Aug 23;16(1):7864. PMID: 40849303 -
Nat Commun
2022 Jun 17;13(1):3486. PMID: 35710796 -
J Exp Clin Cancer Res
GSTK1 suppresses HCC aggravation via L-carnitine metabolism by PGAM5/DRP1 complex-mediated mitochondrial quality control. [Abstract]2025 Nov 24;45(1):1. PMID: 41276823 -
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Int J Biol Sci
Mitochondrial SIRT2-mediated CPT2 deacetylation prevents diabetic cardiomyopathy by impeding cardiac fatty acid oxidation. [Abstract]2025 Jan 1;21(2):725-744. PMID: 39781464 -
Free Radic Biol Med
Carnitine functions as an enhancer of NRF2 to inhibit osteoclastogenesis via regulating macrophage polarization in osteoporosis. [Abstract]2024 Mar:213:174-189. PMID: 38246515 -
Cell Rep
Gasdermin C reprograms metabolism through the CAMKK2-AMPK axis to promote lung adenocarcinoma progression and radioresistance. [Abstract]2026 May 22;45(6):117427. PMID: 42176271 -
Cell Rep
2024 Aug 7;43(8):114591. PMID: 39116204 -
Biosci Rep
Reduction of TMAO level enhances the stability of carotid atherosclerotic plaque through promoting macrophage M2 polarization and efferocytosis. [Abstract]2021 May 28;41(6):BSR20204250. PMID: 33969376 -
Food Sci Biotechnol
Enhancement of the bioactive compounds and biological activities of maca (Lepidium meyenii) via solid-state fermentation with Rhizopus oligosporus. [Abstract]2024 Feb 12;33(11):2585-2596. PMID: 39144202 -
Nutr Metab
Exogenous L-carnitine ameliorates burn-induced cellular and mitochondrial injury of hepatocytes by restoring CPT1 activity. [Abstract]2021 Jun 24;18(1):65. PMID: 34167568 -
J Anim Sci
2022 Apr 1;100(4):skac069. PMID: 35247050 -
Vet Microbiol
The Chinese medicine monomer Schisandrin C inhibits PRRSV infection by regulating the OGT-PI3K/AKT/mTOR signaling pathway. [Abstract]2026 May:316:110992. PMID: 41865607 -
J Chromatogr B Analyt Technol Biomed Life Sci
Simultaneous determination of choline, L-carnitine, betaine, trimethylamine, trimethylamine N-oxide, and creatinine in plasma, liver, and feces of hyperlipidemic rats by UHPLC-MS/MS. [Abstract]2024 Jun 25:1243:124210. PMID: 38936270 -
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Biomed Pharmacother
Interplay of drug transporters P-glycoprotein (MDR1), MRP1, OATP1A2 and OATP1B3 in passage of maraviroc across human placenta. [Abstract]2020 Sep;129:110506. PMID: 32768979 -
Environ Sci Pollut Res Int
2018 Feb;25(4):3765-3774. PMID: 29168138
Solvent & Solubility
H2O : ≥ 100 mg/mL (211.65 mM)
DMSO : 12.5 mg/mL (26.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (281 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Agarwal A, et al. Role of L-carnitine in female infertility. eprod Biol Endocrinol. 2018 Jan 26;16(1):5. [Content Brief]
[2]. Ferreira GC, et al. L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain. Neurochem Res. 2017 Jun;42(6):1661-1675. [Content Brief]
[3]. Uzuner N, et al. The role of L-carnitine in treatment of a murine model of asthma. Acta Med Okayama. 2002 Dec;56(6):295-301. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 2.1165 mL | 10.5825 mL | 21.1649 mL | 52.9123 mL |
| 5 mM | 0.4233 mL | 2.1165 mL | 4.2330 mL | 10.5825 mL | |
| 10 mM | 0.2116 mL | 1.0582 mL | 2.1165 mL | 5.2912 mL | |
| 15 mM | 0.1411 mL | 0.7055 mL | 1.4110 mL | 3.5275 mL | |
| 20 mM | 0.1058 mL | 0.5291 mL | 1.0582 mL | 2.6456 mL | |
| 25 mM | 0.0847 mL | 0.4233 mL | 0.8466 mL | 2.1165 mL | |
| H2O | 30 mM | 0.0705 mL | 0.3527 mL | 0.7055 mL | 1.7637 mL |
| 40 mM | 0.0529 mL | 0.2646 mL | 0.5291 mL | 1.3228 mL | |
| 50 mM | 0.0423 mL | 0.2116 mL | 0.4233 mL | 1.0582 mL | |
| 60 mM | 0.0353 mL | 0.1764 mL | 0.3527 mL | 0.8819 mL | |
| 80 mM | 0.0265 mL | 0.1323 mL | 0.2646 mL | 0.6614 mL | |
| 100 mM | 0.0212 mL | 0.1058 mL | 0.2116 mL | 0.5291 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Carnitine tartrate Related Classifications
HY-W105518 Related Classifications
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