1. Metabolic Enzyme/Protease
    Autophagy
  2. Tyrosinase
    Autophagy

Oxyresveratrol (Synonyms: trans-Oxyresveratrol)

Cat. No.: HY-N1430 Purity: 99.63%
Handling Instructions

Oxyresveratrol is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia.

For research use only. We do not sell to patients.

Oxyresveratrol Chemical Structure

Oxyresveratrol Chemical Structure

CAS No. : 29700-22-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
50 mg USD 60 In-stock
Estimated Time of Arrival: December 31
100 mg USD 84 In-stock
Estimated Time of Arrival: December 31
500 mg USD 312 In-stock
Estimated Time of Arrival: December 31
1 g USD 552 In-stock
Estimated Time of Arrival: December 31
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10 g   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Oxyresveratrol is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia. It effectively scavenges H2O2, NO (IC50 = 45.3 μM), and the artificial free radical 2,2-diphenyl-l-picrylhydrazyl (IC50 = 28.9 μM) In vitro: 1)oxyresveratrol exhibited more than 50% inhibition at 100 μM on L-tyrosine oxidation by murine tyrosinase activity. 2) oxyresveratrol showed an IC50 value of 52.7 μM on the enzyme activity. 3) oxyresveratrol works through reversible inhibition of tyrosinase activity rather than suppression of the expression and synthesis of the enzyme.[2] In vivo: 1) Oxyresveratrol (10 or 20 mg/kg) significantly reduced the brain infarct volume by approximately 54% and 63%, respectively, when compared to vehicle-treated MCAO rats. 2) oxyresveratrol treatment diminished cytochrome c release and decreasedcaspase-3 activation in MCAO rats. [3]

Solvent & Solubility
In Vitro: 

DMSO : ≥ 34 mg/mL (139.21 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0943 mL 20.4717 mL 40.9433 mL
5 mM 0.8189 mL 4.0943 mL 8.1887 mL
10 mM 0.4094 mL 2.0472 mL 4.0943 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

244.24

Formula

C₁₄H₁₂O₄

CAS No.

29700-22-9

SMILES

OC1=CC=C(/C=C/C2=CC(O)=CC(O)=C2)C(O)=C1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Oxyresveratrol
Cat. No.:
HY-N1430
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Oxyresveratrol

Cat. No.: HY-N1430