1. Apoptosis
    Autophagy
  2. Apoptosis
    Autophagy
  3. 3'-Hydroxypterostilbene

3'-Hydroxypterostilbene 

Cat. No.: HY-N6002
Handling Instructions

3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 µM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways.

For research use only. We do not sell to patients.

3'-Hydroxypterostilbene Chemical Structure

3'-Hydroxypterostilbene Chemical Structure

CAS No. : 475231-21-1

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Description

3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 µM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways[1].

IC50 & Target

Apoptosis[1]
Autophagy[1]

Molecular Weight

272.30

Formula

C₁₆H₁₆O₄

CAS No.

475231-21-1

SMILES

COC1=CC(/C=C/C2=CC=C(O)C(O)=C2)=CC(OC)=C1

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3'-Hydroxypterostilbene
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