1. Apoptosis
    Immunology/Inflammation
    Metabolic Enzyme/Protease
  2. TNF Receptor
    Interleukin Related
    Tyrosinase
  3. Mulberroside A

Mulberroside A 

Cat. No.: HY-N0619 Purity: 99.53%
Handling Instructions

Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.). Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory antiapoptotic effects. Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM.

For research use only. We do not sell to patients.

Mulberroside A Chemical Structure

Mulberroside A Chemical Structure

CAS No. : 102841-42-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 143 In-stock
Estimated Time of Arrival: December 31
5 mg USD 114 In-stock
Estimated Time of Arrival: December 31
10 mg USD 180 In-stock
Estimated Time of Arrival: December 31
50 mg USD 540 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Description

Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.)[1]. Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory antiapoptotic effects[2]. Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM[3].

IC50 & Target[1][2][3]

TNF-α

 

IL-1β

 

IL-6

 

Molecular Weight

568.52

Formula

C₂₆H₃₂O₁₄

CAS No.

102841-42-9

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (175.90 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7590 mL 8.7948 mL 17.5895 mL
5 mM 0.3518 mL 1.7590 mL 3.5179 mL
10 mM 0.1759 mL 0.8795 mL 1.7590 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (4.40 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (4.40 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (4.40 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

Mulberroside ATNF ReceptorInterleukin RelatedTyrosinaseTumor Necrosis Factor ReceptorTNFRILInhibitorinhibitorinhibit

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Product Name:
Mulberroside A
Cat. No.:
HY-N0619
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