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  4. Morus alba L.

Morus alba L.

Morus alba L. (32):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0619
    Mulberroside A 102841-42-9 99.92%
    Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.). Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory antiapoptotic effects. Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM.
    Mulberroside A
  • HY-N11849
    Moracin N 135248-05-4 99.74%
    Moracin N is a ferroptosis inhibitor that can be isolated from mulberry leaf. Moracin N exerts neuroprotective activity through preventing from oxidative stress.
    Moracin N
  • HY-N2300
    Kuwanon A 62949-77-3 99.69%
    Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.); inhibits nitric oxide production with an IC50 of 10.5 μM.
    Kuwanon A
  • HY-N12359
    Mulberrofuran B 79295-49-1 99.81%
    Mulberrofuran B can be isolated from the Ethanol extract of Morus alba. Mulberrofuran B has antioxidant activity.
    Mulberrofuran B
  • HY-N3395
    Leachianone G 152464-78-3 99.93%
    Leachianone G is an antiviral flavonoid from the root bark of Morus alba L. Leachianone G shows potent antiviral activity against herpes simplex type 1 virus (HSV-1) with an IC50 value of 1.6 μg/mL.
    Leachianone G
  • HY-N18192
    Kuwanon L 88524-65-6
    Kuwanon L is an HIV-1 integrase (HIV-1 integrase) inhibitor, with IC50 values of 42 μM and 34 μM for LEDGF-dependent and LEDGF-independent integrase, respectively. Kuwanon L blocks the interaction between HIV-1 integrase and LEDGF/p75, with an IC50 of 22 μM. Kuwanon L inhibits HIV-1 replication in immune cells. Kuwanon L is applicable to research related to HIV-1 infection.
    Kuwanon L
  • HY-N16937
    Morusalnol B 1941207-44-8
    Morusalnol B is a natural flavonoid.
    Morusalnol B
  • HY-N17619
    Sanggenofuran A 426211-25-8
    Sanggenofuran A is a natural product that can be found in mulberry.
    Sanggenofuran A
  • HY-N12581
    Kuwanon U 123702-95-4
    Kuwanon U is a potent cholinesterase inhibitor with IC50s of 19.69, 10.11 µM and Kis of 6.48, 9.59 µM for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), respectively. Kuwanon U has the potential for the research of Alzheimer’s disease (AD).
    Kuwanon U
  • HY-N11439
    Albanol B 87084-99-9 99.79%
    Albanol B is an arylbenzofuran derivative which can be isolated from mulberries. Albanol B exhibits anti-Alzheimer's disease, anti-bacterial and antioxidant activities. Albanol B inhibits cancer cells proliferation, down-regulates CDK1 expression. Albanol B also induces cell cycle arrest at G2/M and apoptosis. And Albanol B induces mitochondrial ROS production and increases the phosphorylation levels of AKT and ERK1/2.
    Albanol B
  • HY-12372
    Sanggenon G 85698-31-3
    Sanggenon G is a cell-permeable and potent inhibitor of X-linked inhibitor of apoptosis protein (XIAP). Sanggenon G binds specifically to the BIR3 domain of XIAP with a binding affinity of 34.26 μM. Sanggenon G enhances caspase activation.
    Sanggenon G
  • HY-N11657
    Sanggenon A 76464-71-6
    Sanggenon A (Sanggenone A) exerts anti-inflammatory effects by regulating NF-κB and HO-1/Nrf2 signaling pathways in BV2 and RAW264.7 cells. Sanggenon A markedly inhibits the Lipopolysaccharide (LPS; HY-D1056)-induced production of nitric oxide.
    Sanggenon A
  • HY-N16831
    Moracenin D 78277-79-9
    Moracenin D is a natural flavonoid.
    Moracenin D
  • HY-N16795
    Kuwanon F 71344-07-5
    Kuwanon F is a natural flavonoid.
    Kuwanon F
  • HY-N16798
    Sanggenon M 92280-11-0
    Sanggenon M is a natural phenolic compound.
    Sanggenon M
  • HY-N16796
    Sanggenon I 86450-79-5
    Sanggenon I is a natural flavonoid.
    Sanggenon I
  • HY-N13064
    2,2′,4,4′-Tetrahydroxychalcone 123702-96-5
    2,2′,4,4′-Tetrahydroxychalcone (Compound 18) is a selective and potent BACE1 inhibitor with an IC50 of 0.62 μM. 2,2′,4,4′-Tetrahydroxychalcone is a derivative of Isoliquiritigenin (HY-N0102) found in Glycyrrhiza uralensis. 2,2′,4,4′-Tetrahydroxychalcone can block the β-cutting step of amyloid precursor protein (APP), thereby reducing the production of β-amyloid () peptide. 2,2′,4,4′-Tetrahydroxychalcone can be used for research of Alzheimer’s disease.
    2,2′,4,4′-Tetrahydroxychalcone
  • HY-N11577
    Albafuran C 84323-16-0
    Albafuran C is a natural phenolic compound.
    Albafuran C
  • HY-N16172
    Sanggenon B 81381-67-1
    Sanggenon B (Sanggenone B) is a compound that can be extracted from mulberry trees and has an inhibitory effect on NO production in RAW264.7 cells stimulated by LPS (HY-D1056). Sanggenon B has anti-inflammatory activity.
    Sanggenon B
  • HY-N13009
    MO-2097 2744300-63-6
    MO-2097 is a RAF-1/HIF-1α inhibitor. MO-2097 induces RAF-1 destabilization, leading to a reduction in EMT-associated transcription factors and mesenchymal markers. MO-2097 inhibits HIF-1a protein expression mediated by hnRNPA2B1 under hypoxic and mimetic hypoxia. MO-2097 induces mitochondrial ROS, which leads to apoptosis in cells. MO-2097 effectively suppresses colorectal cancer metastasis by inhibiting the RAF/MEK/ERK signaling pathway. MO-2097 attenuates tumor growth in a xenograft HCT116 cell mouse model. MO-2097 can be used for the study of colorectal cancer.
    MO-2097