2. Anti-infection
  3. HSV
  4. Leachianone G

Leachianone G is an antiviral flavonoid from the root bark of Morus alba L. Leachianone G shows potent antiviral activity against herpes simplex type 1 virus (HSV-1) with an IC50 value of 1.6 μg/mL.

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Leachianone G

Leachianone G Chemical Structure

CAS No. : 152464-78-3

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Description

Leachianone G is an antiviral flavonoid from the root bark of Morus alba L. Leachianone G shows potent antiviral activity against herpes simplex type 1 virus (HSV-1) with an IC50 value of 1.6 μg/mL[1].

IC50 & Target[1]

HSV-1

1.6 μg/mL (IC50)

Molecular Weight

356.37

Formula

C20H20O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C/C(C)=C\CC1=C2C(C(C[C@@H](C3=C(C=C(O)C=C3)O)O2)=O)=C(O)C=C1O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (350.76 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8061 mL 14.0304 mL 28.0607 mL
5 mM 0.5612 mL 2.8061 mL 5.6121 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8061 mL 14.0304 mL 28.0607 mL 70.1518 mL
5 mM 0.5612 mL 2.8061 mL 5.6121 mL 14.0304 mL
10 mM 0.2806 mL 1.4030 mL 2.8061 mL 7.0152 mL
15 mM 0.1871 mL 0.9354 mL 1.8707 mL 4.6768 mL
20 mM 0.1403 mL 0.7015 mL 1.4030 mL 3.5076 mL
25 mM 0.1122 mL 0.5612 mL 1.1224 mL 2.8061 mL
30 mM 0.0935 mL 0.4677 mL 0.9354 mL 2.3384 mL
40 mM 0.0702 mL 0.3508 mL 0.7015 mL 1.7538 mL
50 mM 0.0561 mL 0.2806 mL 0.5612 mL 1.4030 mL
60 mM 0.0468 mL 0.2338 mL 0.4677 mL 1.1692 mL
80 mM 0.0351 mL 0.1754 mL 0.3508 mL 0.8769 mL
100 mM 0.0281 mL 0.1403 mL 0.2806 mL 0.7015 mL
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Leachianone G Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Leachianone G152464-78-3HSVHerpes simplex virusInhibitorinhibitorinhibit

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