88524-65-6
88524-65-6
Chemical Structure
Kuwanon L
- CAS No.: 88524-65-6
- Formula:C35H30O11
- Molecular Weight:626.61
InChIKey: ZEZOBFSLMMTYFF-HQSFFLIMSA-N
SMILES: O=C(C1=C(C=C(C=C1)O)O)[C@@H]2[C@@H](C3=C(C([C@H]4OC5=CC(O)=CC(O)=C5C(C4)=O)=CC=C3O)O)C=C(C[C@H]2C6=C(C=C(C=C6)O)O)C
Biological Activity: Kuwanon L is an HIV-1 integrase (HIV-1 integrase) inhibitor, with IC50 values of 42 μM and 34 μM for LEDGF-dependent and LEDGF-independent integrase, respectively. Kuwanon L blocks the interaction between HIV-1 integrase and LEDGF/p75, with an IC50 of 22 μM. Kuwanon L inhibits HIV-1 replication in immune cells. Kuwanon L is applicable to research related to HIV-1 infection[1].
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Kuwanon L | Kuwanon L is an HIV-1 integrase (HIV-1 integrase) inhibitor, with IC50 values of 42 μM and 34 μM for LEDGF-dependent and LEDGF-independent integrase, respectively. Kuwanon L blocks the interaction between HIV-1 integrase and LEDGF/p75, with an IC50 of 22 μM. Kuwanon L inhibits HIV-1 replication in immune cells. Kuwanon L is applicable to research related to HIV-1 infection. | |||||||||||||||||||||
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