85698-31-3
Chemical Structure
Sanggenon G
- CAS No.: 85698-31-3
- Formula:C40H38O11
- Molecular Weight:694.72
IUPAC Name: (S)-6-((1R,2S,3S)-2-(2,4-dihydroxybenzoyl)-2',4'-dihydroxy-5-(4-methylpent-3-en-1-yl)-1,2,3,6-tetrahydro-[1,1'-biphenyl]-3-yl)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxychroman-4-one
InChIKey: VYCKCQBOVSSJSK-PYQWHEAPSA-N
SMILES: O=C1C[C@@H](C2=CC=C(O)C=C2O)OC3=CC(O)=C([C@H]4C=C(CC/C=C(C)/C)C[C@@H](C5=CC=C(O)C=C5O)[C@@H]4C(C6=CC=C(O)C=C6O)=O)C(O)=C13
Biological Activity: Sanggenon G is a cell-permeable and potent inhibitor of X-linked inhibitor of apoptosis protein (XIAP). Sanggenon G binds specifically to the BIR3 domain of XIAP with a binding affinity of 34.26 μM. Sanggenon G enhances caspase activation[1].
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Sanggenon G | 96.33% | Sanggenon G is a cell-permeable and potent inhibitor of X-linked inhibitor of apoptosis protein (XIAP). Sanggenon G binds specifically to the BIR3 domain of XIAP with a binding affinity of 34.26 μM. Sanggenon G enhances caspase activation. | ||||||||||||||||||||
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Keywords