Glycosyltransferase
Glycosyltransferases (GTs) are key enzymes in the biosynthesis of ginsenosides, which can catalyze the transfer of glycans from donor molecules to acceptor molecules, and form a variety of biologically active glycoside compounds.
All Product Categories
-
Glycosyltransferase Related Products (41)
-
Antibodies (4)
-
Benzyl-α-GalNAc
0 ImagesBenzyl-α-GalNAc is a potent O-glycosylation inhibitor. Benzyl-α-GalNAc effectively inhibits the proliferation and activation of LX-2 cells and suppresses the expression of collagen I/III, which has good potential for investigation in liver fibrosis. Benzyl-α-GalNAc also significantly enhances the anti-tumour activity of 5-Fluorouracil (HY-90006) (e.g. pancreatic cancer) by inhibiting O-glycosylation. -
loading...loading...
-
-
2-Deoxy-2-fluoro-L-fucose
0 Images2-Deoxy-2-fluoro-L-fucose, an L-fucose analog, is a fucosylation inhibitor. 2-Deoxy-2-fluoro-L-fucose inhibits de novo synthesis of GDP-fucose in mammalian cells. Fucosylation is a relatively well-defined biomarker for progression in many human cancers; for example, pancreatic and hepatocellular carcinoma. -
loading...loading...
-
-
2F-Peracetyl-Fucose
0 ImagesSynonyms: 1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) acts as a potent fucosyltransferase (FUT) inhibitor. -
loading...loading...
-
-
MZ-101
0 ImagesSynonyms: GYS1-IN-2MZ-101 (GYS1-IN-2) is an orally active, potent and selective small-molecule glycogen synthase 1 (GYS1) inhibitor with with an IC50 value of 0.041 µM. MZ-101 reduces glycogen concentrations in cells and in mice. MZ-101 can used to study GYS1 -mediated Pompe disease and other glycogen storage diseases. -
loading...loading...
-
-
SGN-2FF
0 ImagesSGN-2FF is a potent and orally active inhibitor of fucosylation, directly inhibits fucosyltransferase activity. SGN-2FF possesses antitumor activity. -
loading...loading...
-
-
1,3-β-Oligoglucan phosphorylase
0 ImagesCat. No.: HY-E711551,3-β-Oligoglucan phosphorylase (EC 2.4.1.30) belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The two substrates of this enzyme are (1,3-beta-D-glucosyl) n and phosphate, whereas its two products are (1,3-beta-D-glucosyl) n-1 and alpha-D-glucose 1-phosphate. -
loading...loading...
-
- 1,3-β-Glucan synthase
-
loading...loading...
-
-
α,α-Trehalose phosphorylase
0 ImagesCat. No.: HY-E71206α,α-Trehalose phosphorylase (EC 2.4.1.64) belongs to the family of glycosyltransferases, specifically the hexosyltransferases. -
loading...loading...
-
- SU0268
-
loading...loading...
-
-
T3Inh-1
0 ImagesT3Inh-1 is a potent and selective inhibitor of ppGalNAc-T3 (IC50=7 μM). T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic side effects. T3Inh-1 also prevents breast cancer cells. The enzyme ppGalNAc-T3 is implicated in at least two medically important pathways: cancer metastasis and stabilization of FGF23 (regulates phosphate levels in the bloodstream). -
loading...loading...
-
-
12-Hydroxyjasmonic acid
0 Images12-Hydroxyjasmonic acid is a metabolite of Jasmonic acid (HY-122464A) and an inducer of defense responses. 12-Hydroxyjasmonic acid can be isolated from potato leaflets. During the response of sugar beet plants to Cercospora beticola infection, 12-Hydroxyjasmonic acid is released through deglycosylation of its glucoside form and participates in the Jasmonic acid-mediated defense signaling pathway. 12-Hydroxyjasmonic acid mediates changes in source-sink relationships during pathogen infection, prioritizing the activation of defense processes over growth processes. 12-Hydroxyjasmonic acid serves as a substrate for salicylic acid Glycosyltransferases in tobacco and rice. 12-Hydroxyjasmonic acid can induce leaflet closure in Samanea saman. 12-Hydroxyjasmonic acid acts as a potato tuber-inducing substance. 12-Hydroxyjasmonic acid does not induce protoplast shrinkage in extensor motor cells of Samanea saman. 12-Hydroxyjasmonic acid can be used in studies related to brown spot disease. -
loading...loading...
-
-
AG-205
0 ImagesAG-205 is a progesterone receptor membrane component 1 (PGRMC1) antagonist and CGT inhibitor, with an IC50 of 50 μM against rat CGT. AG-205 exhibits antimitotic, antimigratory and anti-invasive activities. AG-205 increases the expression of genes encoding cholesterol biosynthesis pathway or steroidogenic enzymes. AG-205 promotes the regulation of cell cycle by apoptosis and reduces the migratory and invasive capacities of ovarian and breast cancer cells. AG-205 can be used in research related to renal cancer and breast cancer. -
loading...loading...
-
-
yGsy2p-IN-1
0 ImagesyGsy2p-IN-1 is a potent inhibitor for yeast glycogen synthase 2 (yGsy2p). yGsy2p-IN-1 is a competitive human glycogen synthase 1 (hGYS1) inhibitor with an IC50 of 2.75 μM and a Ki of 1.31 μM for wild-type hGYS1. yGsy2p-IN-H23 a pyrazole inhibitor, is used for glycogen storage diseases (GSDs). -
loading...loading...
-
-
alpha-1,4-Galactosyltransferase (LgtC)
0 ImagesCat. No.: HY-E70047CAS No.: 52725-57-2Synonyms: A4GALTalpha-1,4-Galactosyltransferase (LgtC) (A4GALT) is a glycosphingolipid-specific glycosyltransferase. alpha-1,4-Galactosyltransferase (LgtC) transfers a galactose to the alpha-1,4 position of lactosylceramide to form globotriaosylceramide. alpha-1,4-Galactosyltransferase (LgtC) can be used for the synthesis of P1 blood group antigens. -
loading...loading...
-
-
AJS1669 free acid
0 ImagesAJS1669 free acid is a potent and orally available glycogen synthase (GS) activator. AJS1669 improves glucose metabolism and reduces body fat mass in mice[1]. -
loading...loading...
-
-
PST3.1a
0 ImagesCat. No.: HY-163121CAS No.: 1096144-06-7PST3.1a is an orally active and brain-penetrant N-acetylglucosamine glycosyltransferase (MGAT5) inhibitor with a human IC50 of 2 µM. PST3.1a inhibits TGFβR and FAK signaling pathway activity. PST3.1a alters β1,6-GlcNAc N-glycans and microtubule/microfilament integrity, increases OLIG2 expression, and inhibits proliferation, migration, invasiveness, and clonogenic capacities of glioblastoma initiating cells. PST3.1a reduces invasive and proliferative capacity of glioblastoma initiating cells in orthotopic graft models, increases overall survival of orthotopic graft model mice. PST3.1a blunts MGAT5 overexpression, decreases renal fibrosis via collagen 1, collagen 4, and galectin 3 downregulation in a rat chronic kidney disease model. PST3.1a can be used for the research of glioblastoma multiforme and chronic kidney disease. -
loading...loading...
-
- β-1,4-Galactosyltransferase 2
-
loading...loading...
-
-
Iliparcil
0 ImagesIliparcil has a potent antithrombotic activity in the Wessler model in rats. Iliparcil has oral activity. -
loading...loading...
-
- β-1,4-Galactosyltransferase 7
-
loading...loading...
-
-
beta-1, 3-N-Acetylhexaminyltransferase (LgtA)
0 ImagesCat. No.: HY-E70044CAS No.: 37277-64-8beta-1, 3-N-Acetylhexaminyltransferase (LgtA) is a glycosyltransferase, is often used in biochemical studies. beta-1, 3-N-Acetylhexaminyltransferase (LgtA) catalyzes the transfer of N-acetylglucosamine from UDP-GlcNAc to N-acetyllactosamine and lactose. -
loading...loading...
-
