Bovin beta-1,4-galactosyltransferase 1 (Y289L) (Synonyms: Bovin B4GALT1 (Y289L))

Cat. No.: HY-E70289: FAQs
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Bovin beta-1,4-galactosyltransferase 1 (Y289L) (Bovin B4GALT1 (Y289L)) is a mutated form of bovine-derived galactosyltransferase with a mutation at the Y289L genetic site. Bovin beta-1,4-galactosyltransferase 1 can label O-GlcNAcylated proteins with an N-azidoacetylgalactosamine (GalNAz) group. This labeling method allows for the specific, unbiased, and global labeling of O-GlcNAcylated proteins. After labeling, the appended azide group can react with a wide variety of alkyne-modified chemical probes, facilitating multiple downstream analyses.

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Bovin beta-1,4-galactosyltransferase 1 (Y289L) Chemical Structure

Size	Stock
1 mg	Get quote	Estimated Time of Arrival: December 31
20 µ g	Get quote	Estimated Time of Arrival: December 31
100 µ g	Get quote	Estimated Time of Arrival: December 31

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Description	Bovin beta-1,4-galactosyltransferase 1 (Y289L) (Bovin B4GALT1 (Y289L)) is a mutated form of bovine-derived galactosyltransferase with a mutation at the Y289L genetic site. Bovin beta-1,4-galactosyltransferase 1 can label O-GlcNAcylated proteins with an N-azidoacetylgalactosamine (GalNAz) group. This labeling method allows for the specific, unbiased, and global labeling of O-GlcNAcylated proteins. After labeling, the appended azide group can react with a wide variety of alkyne-modified chemical probes, facilitating multiple downstream analyses^[1].
SMILES	[Bovin beta-1,4-galactosyltransferase 1 (Y289L)]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (263 KB) Handling Instructions (2659 KB)
References	[1]. Thompson JW, et al. Methods for the Detection, Study, and Dynamic Profiling of O-GlcNAc Glycosylation. Methods Enzymol. 2018;598:101-135. [Content Brief]

Bovin beta-1,4-galactosyltransferase 1 (Y289L) Related Classifications

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bovin beta-1,4-galactosyltransferase 1 (Y289L)Bovin B4GALT1 (Y289L)Endogenous Metabolitechemical enzyme labeling methodO-GlcNAcylatedInhibitorinhibitorinhibit

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Bovin beta-1,4-galactosyltransferase 1 (Y289L) (Synonyms: Bovin B4GALT1 (Y289L))

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