- Signaling Pathways
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- Glycosyltransferase
Glycosyltransferase
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Glycosyltransferase Related Products (55)
Related Products (55)
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Antibodies (4)
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α,α-Trehalose phosphorylase
0 ImagesCat. No.: HY-E71206α,α-Trehalose phosphorylase (EC 2.4.1.64) belongs to the family of glycosyltransferases, specifically the hexosyltransferases. -
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- Fucosyltransferase 3
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2-Deoxy-2-fluoro-L-fucose (GMP)
0 ImagesCat. No.: HY-116705GCAS No.: 70763-62-1Synonyms: 2-Fluorofucose (GMP)2-Deoxy-2-fluoro-L-fucose (2-Fluorofucose) GMP is a fucosyltransferase inhibitor that inhibits core fucosylation modification in cells. 2-Deoxy-2-fluoro-L-fucose GMP promotes the production of defucosylated IgG1 antibodies in IgG1-expressing cell culture systems; it regulates the levels of inflammatory cytokines such as IL-1β, IL-6 and TGF-β in human induced pluripotent stem cell-derived microglia. 2-Deoxy-2-fluoro-L-fucose GMP can be used in the research of related diseases including dengue fever and Alzheimer's disease. -
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- 1,4-α-Glucan 6-α-glucosyltransferase
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TM-Cy-TBPA
0 ImagesCat. No.: HY-187701TM-Cy-TBPA is a selective inhibitor of mammalian dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) with an IC50 of 0.034 μM. TM-Cy-TBPA inhibits breast cancer cell proliferation via G2 phase arrest and apoptosis. TM-Cy-TBPA can be used for the research of metastatic breast cancer. -
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- beta-1,4-Galactosyltransferase (LgtE)
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Sucrose synthase
0 ImagesSucrose synthase belongs to glycosyltransferases and is a reversible catalyst present in plants, which catalyzes the conversion of sucrose into fructose and UDP-G or ADP-G. Sucrose synthase localizes to the cytoplasm, plasma membrane, cell wall, vacuole and mitochondria of plants. Sucrose synthase regulates sugar metabolism, supports the development of taproots, fruits, seeds and vascular tissues, drives the synthesis of starch, cellulose and callose, and enhances nitrogen fixation capacity. Sucrose synthase mediates signal transduction in plant meristems. Sucrose synthase is associated with plant growth, anaerobic stress tolerance, as well as shoot apical meristem and leaf morphology; overexpression of this enzyme promotes plant growth, increases xylem size, and elevates cellulose and starch contents. -
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Fucosyltransferase 11
0 ImagesCat. No.: HY-E70159Synonyms: FUT11Fucosyltransferase 11 (EC:2.4.1.-, FUT11) links alpha-l-fucose onto conalbumin glycopeptides and biantennary N-glycan acceptors. Fucosyltransferase 11 plays an important role in cancer. -
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Endosidin7
0 ImagesCat. No.: HY-182408CAS No.: 329072-88-0Endosidin7 is a specific inhibitor for plant callose deposition during cytokinesis. Endosidin7 inhibits cytokinesis-specific callose deposition at the cell plate, disrupts cell plate maturation, and alters localization of cell plate-associated proteins during late cell plate development. Endosidin7 slows root growth and induces formation of cell wall stubs in Arabidopsis thaliana seedlings. -
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UDP-GlcNAc
0 ImagesSynonyms: UDP-N-Acetyl-D-glucosamine; Uridine diphospho-N-acetylglucosamine; UDP-N-acetylglucosamineUDP-GlcNAc (UDP-N-Acetyl-D-glucosamine) is an important component and precursor of bacterial peptidoglycan. UDP-GlcNAc is a nucleotide sugar used by Glycosyltransferases to synthesize glycoproteins, glycosaminoglycans, glycolipids, and glycoRNA. UDP-GlcNAc also serves as the donor substrate for forming O-GlcNAc, a dynamic intracellular protein modification involved in diverse signaling and disease processes. UDP-GlcNAc is the sugar nucleotide donor for the synthesis of O-GlcNAc modified proteins. UDP-GlcNAc also acts as a full agonist of the P2Y14 receptor and inhibits the formation of cAMP. UDP-GlcNAc can be used in studies related to bacterial infections. -
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Glycosyltransferase-IN-1
0 ImagesCat. No.: HY-147960CAS No.: 3037663-79-6Glycosyltransferase-IN-1 (compound 5m) is a potent glycosyltransferase inhibitor, with an IC50 of 82.8 μM. Glycosyltransferase-IN-1 shows antibacterial activity, with MIC values of 6 μg/mL for MSSA, MRSA, B. subtilis and 12 μg/mL for E. coli. -
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Glycosyltransferase-IN-2
0 ImagesCat. No.: HY-175697Glycosyltransferase-IN-2 (Compound 20) is a Glycosyltransferase inhibitor. Glycosyltransferase-IN-2 has a broad-spectrum anticoronavirus activity with IC50s of 11.3, 5.5 and ~16.2 μM for MHV, HCoV-NL63 and SARS-CoV-2, respectively. Glycosyltransferase-IN-2 interferes with the coronavirus infectivity, alters viral protein glycosylation with inhibition of interaction with the ACE2 receptor or SC-VLP secretion, and inhibits RNA replication. Glycosyltransferase-IN-2 can be used for coronavirus infections research. -
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Benzyl-α-GalNAc (Standard)
0 ImagesCat. No.: HY-129389RCAS No.: 3554-93-6Benzyl-α-GalNAc (Standard) is the analytical standard of Benzyl-α-GalNAc (HY-129389). This product is intended for research and analytical applications. Benzyl-α-GalNAc is a potent O-glycosylation inhibitor. Benzyl-α-GalNAc effectively inhibits the proliferation and activation of LX-2 cells and suppresses the expression of collagen I/III, which has good potential for investigation in liver fibrosis. Benzyl-α-GalNAc also significantly enhances the anti-tumour activity of 5-Fluorouracil (HY-90006) (e.g. pancreatic cancer) by inhibiting O-glycosylation. -
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UDP-Galactosamine
0 ImagesCat. No.: HY-W1139983ACAS No.: 17479-06-0UDP-Galactosamine is a sugar nucleotide donor and enzyme substrate, exhibiting activity toward Galactosyltransferase, UDP-galactose 4'-epimerase, and hexose-1-phosphate uridylyltransferase. UDP-Galactosamine supports the transfer of galactosamine residues to acceptor molecules and participates in the biosynthesis of UDP-galactose. UDP-Galactosamine enables a two-step chemoenzymatic preparative-scale synthesis of GalNAc-glycosides and derivatives with unnatural glycosidic linkages . -
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SGN-2FF (Standard)
0 ImagesCat. No.: HY-107366RCAS No.: 2089647-47-0 -
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