2. Recombinant Proteins
  3. Immune Checkpoint Proteins
  4. Inhibitory Checkpoint Molecules
  5. NTB-A

NTB-A

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Cat. No. Product Name / Synonyms Species Source
  • HY-P71317
    SLAMF6 Protein, Human (198a.a, HEK293, His)

    SLAM Family Member 6; Activating NK Receptor; NK-T-B-Antigen; NTB-A; CD352; SLAMF6; KALI

    		Human HEK293
    SLAMF6 protein is an autoligand receptor in the SLAM family, which is critical for the activation and differentiation of immune cells and coordinates innate and adaptive immune responses. SLAMF6 is regulated by cytoplasmic adapters such as SH2D1A/SAP and/or SH2D1B/EAT-2, and can trigger the cytolytic activity of NK cells, including VAV1 phosphorylation and SH2D1B dependence. SLAMF6 Protein, Human (198a.a, HEK293, His) is the recombinant human-derived SLAMF6 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SLAMF6 Protein, Human (198a.a, HEK293, His) is 198 a.a., with molecular weight of 30-50 kDa.
  • HY-P76076
    SLAMF6 Protein, Mouse (HEK293, His)

    SLAM Family Member 6; Activating NK Receptor; NK-T-B-Antigen; NTB-A; CD352; SLAMF6; KALI

    		Mouse HEK293
    SLAMF6 protein is a self-ligand receptor in the SLAM family, which complexly regulates the activation and differentiation of immune cells through homotypic or heterotypic interactions, affecting innate and adaptive immune responses. It relies on cytoplasmic adapters such as SH2D1A/SAP and/or SH2D1B/EAT-2 for activity control. SLAMF6 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SLAMF6 protein, expressed by HEK293 , with C-His labeled tag. The total length of SLAMF6 Protein, Mouse (HEK293, His) is 209 a.a., with molecular weight of ~28-50 kDa.
  • HY-P76647
    SLAMF6 Protein, Human (226a.a, HEK293, His)

    SLAM Family Member 6; Activating NK Receptor; NK-T-B-Antigen; NTB-A; CD352; KALIf

    		Human HEK293
    SLAMF6 protein is an autoligand receptor in the SLAM family, which is critical for the activation and differentiation of immune cells and coordinates innate and adaptive immune responses. SLAMF6 is regulated by cytoplasmic adapters such as SH2D1A/SAP and/or SH2D1B/EAT-2, and can trigger the cytolytic activity of NK cells, including VAV1 phosphorylation and SH2D1B dependence. SLAMF6 Protein, Human (226a.a, HEK293, His) is the recombinant human-derived SLAMF6 protein, expressed by HEK293 , with C-His labeled tag. The total length of SLAMF6 Protein, Human (226a.a, HEK293, His) is 226 a.a., with molecular weight of 38-40 kDa.
  • HY-P72415
    SLAMF6 Protein, Human (HEK293, His-Avi)

    SLAM Family Member 6; Activating NK Receptor; NK-T-B-Antigen; NTB-A; CD352; SLAMF6; KALI

    		Human HEK293
    SLAMF6 Protein, a self-ligand receptor in the SLAM family, crucially modulates immune cell activation and differentiation, orchestrating innate and adaptive immune responses. Regulated by cytoplasmic adapters like SH2D1A/SAP and/or SH2D1B/EAT-2, SLAMF6 triggers NK cell cytolytic activity, involving VAV1 phosphorylation and SH2D1B dependence. Teaming with SLAMF1, it guides thymocytic NKT cell lineage transition. SLAMF6 promotes Th17 differentiation, potentially negatively regulates humoral immune response, and, in the absence of SH2D1A/SAP, transmits negative signals to CD4(+) T-cells and NKT cells, inhibiting germinal center formation and contributing to B-cell tolerance. SLAMF6, existing as a homodimer, interacts with PTN6, PTN11, SH2D1A/SAP, and SH2D1B/EAT2. Both adapter proteins can associate with the same SLAMF6 molecule, mediated by ITSM 2. SLAMF6 Protein, Human (HEK293, His-Avi) is the recombinant human-derived SLAMF6 protein, expressed by HEK293, with C-Avi, C-6*His labeled tag. The total length of SLAMF6 Protein, Human (HEK293, His-Avi) is 204 a.a., with molecular weight of 35-50 kDa.
  • HY-P76645
    SLAMF6 Protein, Human (HEK293)

    SLAM Family Member 6; Activating NK Receptor; NK-T-B-Antigen; NTB-A; CD352; KALIf

    		Human HEK293
    SLAMF6 protein is an autoligand receptor in the SLAM family, which is critical for the activation and differentiation of immune cells and coordinates innate and adaptive immune responses. SLAMF6 is regulated by cytoplasmic adapters such as SH2D1A/SAP and/or SH2D1B/EAT-2, and can trigger the cytolytic activity of NK cells, including VAV1 phosphorylation and SH2D1B dependence. SLAMF6 Protein, Human (HEK293) is the recombinant human-derived SLAMF6 protein, expressed by HEK293 , with tag free. The total length of SLAMF6 Protein, Human (HEK293) is 226 a.a., with molecular weight of 37-43 kDa.
  • HY-P76646
    SLAMF6 Protein, Human (HEK293, Fc)

    SLAM Family Member 6; Activating NK Receptor; NK-T-B-Antigen; NTB-A; CD352; KALIf

    		Human HEK293
    SLAMF6 protein is an autoligand receptor in the SLAM family, which is critical for the activation and differentiation of immune cells and coordinates innate and adaptive immune responses. SLAMF6 is regulated by cytoplasmic adapters such as SH2D1A/SAP and/or SH2D1B/EAT-2, and can trigger the cytolytic activity of NK cells, including VAV1 phosphorylation and SH2D1B dependence. SLAMF6 Protein, Human (HEK293, Fc) is the recombinant human-derived SLAMF6 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of SLAMF6 Protein, Human (HEK293, Fc) is 226 a.a., with molecular weight of 63-68 kDa.
  • HY-P78357
    SLAMF6 Protein, Mouse (HEK293, Fc)

    ANK-T-B-antigen; NTB-A; CD352; SLAMF6; KALI; Ly108; NK-T-B-antigen; KALIb; SF2000

    		Mouse HEK293
    SLAMF6 protein is a self-ligand receptor in the SLAM family, which complexly regulates the activation and differentiation of immune cells through homotypic or heterotypic interactions, affecting innate and adaptive immune responses. It relies on cytoplasmic adapters such as SH2D1A/SAP and/or SH2D1B/EAT-2 for activity control. SLAMF6 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived SLAMF6 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of SLAMF6 Protein, Mouse (HEK293, Fc) is 209 a.a., with molecular weight of 65-75 kDa.
  • HY-P700828
    SLAMF6 Protein, Cynomolgus (HEK293, His)

    ANK-T-B-antigen; NTB-A; CD352; SLAMF6; KALI; Ly108; NK-T-B-antigen; KALIb; SF2000

    		Cynomolgus HEK293
    SLAMF6 protein is a self-ligand receptor in the SLAM family, which complexly regulates the activation and differentiation of immune cells through homotypic or heterotypic interactions, affecting innate and adaptive immune responses. It relies on cytoplasmic adapters such as SH2D1A/SAP and/or SH2D1B/EAT-2 for activity control. SLAMF6 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived SLAMF6 protein, expressed by HEK293 , with C-His labeled tag. The total length of SLAMF6 Protein, Cynomolgus (HEK293, His) is 206 a.a., with molecular weight of 37-50 kDa.
Cat. No. Product Name Effect Purity