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Dynasore

100 Cited Publications
Customer Review

Based on 100 publication(s) in Google Scholar

Dynasore is a cell-permeable dynamin inhibitor with an IC50 of 15 μM. Dynasore blocks cell migration.

For research use only. We do not sell to patients.

  • Purity: 99.77%
  • CAS No.: 304448-55-3
  • Formula: C18H14N2O4
  • Molecular Weight:322.31
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Dynasore Chemical Structure
    Dynasore Chemical Structure
  • Experimental Validation Results for Dynasore
  • Experimental Validation Results for Dynasore
  • Experimental Validation Results for Dynasore
  • Experimental Validation Results for Dynasore
  • Experimental Validation Results for Dynasore
  • Experimental Validation Results for Dynasore
CAS No.: 304448-55-3
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609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • Dynasore Chemical Structure
    Dynasore Chemical Structure
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    Dynasore purchased from MedChemExpress. Usage Cited in: Adv Mater. 2025 Mar;37(9):e2415030. [Abstract]

    Customer Validation
     Dynasore （50 µg/mL， 7 h）. FCM analysis of F/G/H‐GNC internalization by 4T1 cells pre‐treated with various endocytosis inhibitors (n = 3).

  • 1/16

    Dynasore purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Nov 13;16(1):9973. [Abstract]

    Customer Validation
     Immunofluorescence (IF) analysis of GFP-tagged IR (green) and RAB7 (red) in HepG2 cells transfected with various siRNAs or treated with dynasore (50 μM for 4 h) as indicated.

  • 1/16

    Dynasore purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Nov 13;16(1):9973. [Abstract]

    Customer Validation
     Co-immunoprecipitation (co-IP) assay showing the interaction between IRβ and AP2B1 in WT and DJ2−/− 4T1 cells treated with 50 μM dynasore for 4 h. The red arrow indicates DNAJA2 band.

  • 1/16

    Dynasore purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2024 Sep 26;9(1):254. [Abstract]

    Customer Validation
     N2a cells expressing Cadm4 or Cadm4-C347A were treated with Dynasore(80 μM, 12 h) for preparing plasma membrane fractions, which were evaluated by WB.

  • 1/16

    Dynasore purchased from MedChemExpress. Usage Cited in: J Extracell Vesicles. 2021 Jul;10(9):e12117. [Abstract]

    Customer Validation
     Fluorescence images showing uptake of labelled SEVs by HPMECs in the presence or absence of the EV uptake inhibitor Dynasore (10 μM, 30 min).

  • 1/16

    Dynasore purchased from MedChemExpress. Usage Cited in: J Am Chem Soc. 2018 Dec 12;140(49):17234-17240. [Abstract]

    Customer Validation
     HEK 293 cells are treated with different concentrations of Dynasore for indicated time. Then, the treated cells are collected and Western blot analysis is performed with indicated antibodies to detect LC3-I and LC3-II. GAPDH serves as the loading control.

  • Dynasore