20 Results for "

il-17ra

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "il-17ra" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P9924
CAS No.: 1143503-69-8
Synonyms: LY2439821

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A (KD<3 pM). Ixekizumab directly blocks IL-17A binding to IL-17RA (IL-17A receptor) but does not bind to other IL-17 family members. Ixekizumab is used for the research of moderate-to-severe plaque psoriasis .
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1
1 Cited Publications
Cat. No.: HY-P71963
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CANDF5; CD217; CD217 antigen; CDw217; CTLA8; Hil 17R; hil17R; I17ra_HUMAN; il 17 receptor A; il 17 receptor; il 17ra; il-17 receptor A; il-17ra; il17; il17A receptor; il17R; il17ra; IMD51; Interleukin 17 receptor A; Interleukin-17 receptor A; MGC10262
Species:  
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Cat. No.: HY-P991266

Research Areas:  

Inflammation/Immunology

SM-17 is a human monoclonal antibody targeting IL-17RB. SM-17 binds to human IL-17RB, inhibits the dimerization of IL-17RA/IL-17RB, blocks IL-25-induced phosphorylation of ERK1/2 and STAT5, and suppresses Th2-mediated inflammatory responses. SM-17 inhibits the secretion of IL-5, IL-9, IL-13 and IL-4, impairs the proliferation/expansion of ILC2 and Th2 cells, and restores filaggrin expression. SM-17 reduces immune cell infiltration, epidermal hyperplasia, goblet cell hyperplasia, collagen deposition, ear swelling and scratching behavior in animal models. SM-17 can be used in research related to atopic dermatitis and allergic asthma .
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Cat. No.: HY-RS06702
Research Areas:  

Others

IL17RA Human Pre-designed siRNA Set A contains three designed siRNAs for IL17RA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174632
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL17RA mRNA encodes the human interleukin 17 receptor subunit alpha (IL17RA) protein, a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.
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Cat. No.: HY-178714
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

JNJ627 is a small molecule allosteric inhibitor of IL-17A with a KD of 92 nM. JNJ627 effectively inhibits the binding of IL-17A and IL-17RA, with an IC50 value of 16 nM. JNJ627 is capable of inhibiting the secretion of G-CSF (granulocyte colony-stimulating factor) caused by IL-17A stimulation. JNJ627 can be used for the study of autoimmune diseases (such as psoriasis) .
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Cat. No.: HY-RS18197
Research Areas:  

Others

Il17ra Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il17ra gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24671
Research Areas:  

Others

Il17ra Rat Pre-designed siRNA Set A contains three designed siRNAs for Il17ra gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P82900
Synonyms: il17ra; il17R; Interleukin-17 receptor A; il-17 receptor A; il-17ra; CDw217; CD antigen CD217

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human

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Cat. No.: HY-P74825
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-17 receptor A; il-17ra; CDw217; CD217; il17R
Species:  
Rat
Source:  
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Cat. No.: HY-P74826
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-17 receptor A; il-17ra; CDw217; CD217; il17R
Species:  
Rat
Source:  
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Cat. No.: HY-P74827
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-17 receptor A; il-17ra; CDw217; CD217; il17R
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Cat. No.: HY-P76992
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-17 receptor A; il-17ra; CDw217; CD217; il17R
Species:  
Source:  
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Cat. No.: HY-P76991
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-17 receptor A; il-17ra; CDw217; CD217; il17R
Species:  
Source:  
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Cat. No.: HY-P81634
Synonyms: il17ra; il17R; Interleukin-17 receptor A; il-17 receptor A; il-17ra; CDw217; CD antigen CD217

Host:  

Rabbit

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P72583
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-17 receptor A; il-17 receptor A; CDw217; CD217; il17ra; il17R
Species:  
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Cat. No.: HY-P78147
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD217; CDw217; il-17ra; il17R; CANDF5; il-7R; il-7R-alpha; ilRA
Species:  
Source:  
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Cat. No.: HY-P78161
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD217; CDw217; il-17ra; il17R; CANDF5; il-7R; il-7R-alpha; ilRA
Species:  
Source:  
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Cat. No.: HY-P704696
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: il-17 RA & il-17 RC; il-17ra & il-17RC; CD217 & il-17 RC
Species:  
Source:  
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Cat. No.: HY-P70892
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADP-ribosyl cyclase 1; cyclic ADP-ribose hydrolase; CD38; T10
Species:  
Source:  
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