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Results for "

muscle-specific-kinase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	nAChR (1)
By Research Areas:	Neurological Disease (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P991066

Adimanebart ARGX-119	nAChR	Neurological Disease
ARGX-119 is a first-in-class humanized agonist monoclonal antibody specific for muscle-specific kinase (MuSK). ARGX-119 can be used for the study of neuromuscular diseases. The isotype control for ARGX-119 can refer to Human IgG1 lambda1, Isotype Control (HY-P99992) .

Cat. No.	Product Name	Target	Research Area	Image

HY-P991066

Adimanebart ARGX-119	nAChR	Neurological Disease
ARGX-119 is a first-in-class humanized agonist monoclonal antibody specific for muscle-specific kinase (MuSK). ARGX-119 can be used for the study of neuromuscular diseases. The isotype control for ARGX-119 can refer to Human IgG1 lambda1, Isotype Control (HY-P99992) .

Recombinant Proteins Recommended:

Muscle-Specific Kinase (MuSK)

Species:	Human (1) Mouse (2)
Tag:	SUMO (1) His (3) Myc (1)
Source:	HEK293 (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P703959

	MUSK Protein, Human (HEK293, His) EC:2.7.10.1; MuSK; muscle-specific kinase receptor	Human	HEK293
	MUSK protein is a receptor tyrosine kinase that plays a crucial role in the formation and maintenance of the neuromuscular junction (NMJ). After LRP4 recruits AGRIN, MUSK phosphorylates and activates, affecting gene expression, coordinating actin cytoskeletal reorganization, and clustering acetylcholine receptors (AChR) in the postsynaptic membrane. MUSK Protein, Human (HEK293, His) is the recombinant human-derived MUSK protein, expressed by HEK293, with C-His labeled tag.

HY-P703958

	MUSK Protein, Mouse (HEK293, His) EC:2.7.10.1; MuSK; muscle-specific kinase receptor	Mouse	HEK293
	MUSK protein is a receptor tyrosine kinase that plays a critical role in the formation of the neuromuscular junction (NMJ). MUSK is activated by the AGRIN-LRP4 complex and regulates the NMJ through gene expression, actin cytoskeleton reorganization, and acetylcholine receptor (AChR) clustering. MUSK Protein, Mouse (HEK293, His) is the recombinant mouse-derived MUSK protein, expressed by HEK293, with C-His labeled tag.

HY-P71568

	MUSK Protein, Mouse (Myc, His-SUMO) Musk; Nsk2; muscle; skeletal receptor tyrosine-protein kinase; EC 2.7.10.1; muscle-specific tyrosine-protein kinase receptor; MuSK; muscle-specific kinase receptor	Mouse	E. coli
	MUSK protein is a receptor tyrosine kinase that plays a critical role in the formation of the neuromuscular junction (NMJ).MUSK is activated by the AGRIN-LRP4 complex and regulates the NMJ through gene expression, actin cytoskeleton reorganization, and acetylcholine receptor (AChR) clustering.MUSK Protein, Mouse (Myc, His-SUMO) is the recombinant mouse-derived MUSK protein, expressed by E.coli , with C-Myc, N-SUMO, N-10*His labeled tag.

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Host:	Mouse (2)
Reactivity:	Human (2)
Application:	IHC-P (2) ICC/IF (2) ELISA (2)
Isotype:	IgG1 (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1)
Modification:	Unmodified (1)

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HY-P85288

	MuSK Antibody (YA4980) MUSK; muscle; skeletal receptor tyrosine-protein kinase; muscle-specific tyrosine-protein kinase receptor; MuSK; muscle-specific kinase receptor	IHC-P, ICC/IF, ELISA	Human
	MuSK Antibody (YA4980) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MuSK.

HY-P85288A

	MuSK Antibody (YA4980)(PBS only) MUSK; muscle; skeletal receptor tyrosine-protein kinase; muscle-specific tyrosine-protein kinase receptor; MuSK; muscle-specific kinase receptor	IHC-P, ICC/IF, ELISA	Human
	MuSK Antibody (YA4980) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MuSK.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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