AldRed 588-A 

AldeRed 588-A is a fluorescent labeling reagent and a substrate for aldehyde dehydrogenase (ALDH). AldeRed 588-A is metabolized by functionally active ALDH enzymes, thereby specifically labeling viable ALDH^bright cell populations with red-shifted fluorescence. AldeRed 588-A supports one-step isolation and sorting of ALDH-expressing cells (including normal stem cells and cancer stem cells), and can be used in combination with green fluorophores for multicolor experimental applications. AldeRed 588-A is widely applicable to research related to various cancers such as bladder cancer, breast cancer, and head and neck cancer^[1][2].

AldRed 588-A identifies ALDH^bright cell populations in cell lines expressing functional ALDH with potency comparable to that of ALDEFLUOR^TM, and enables one-step isolation of ALDH-expressing cells when co-incubated with ALDEFLUOR^TM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

370.16

C₁₈H₁₇BF₂N₄O₂

2252329-12-5

O=CCNC(CCC1=[N]2[B+3]([F-])([F-])[N-]3C(C4=CC=CN4)=CC=C3C=C2C=C1)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Dollé L, et al. Next generation of ALDH substrates and their potential to study maturational lineage biology in stem and progenitor cells. Am J Physiol Gastrointest Liver Physiol. 2015;308(7):G573-G578.

  [2]. Asbrock N, et al. A red-shifted fluorescent substrate for aldehyde dehydrogenase, AldeRed 588-A, for labeling viable ALDH-positive cells[J]. Cancer Research, 2016, 76(14_Supplement): 2508-2508.