Methyltetrazine-Ph-NHS ester
Based on 1 Customer Validation
Methyltetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. Methyltetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.94%
- CAS. Nr.: 1644644-96-1
- Formel: C15H13N5O4
- Molecular Weight:327.29
-
Speicherung:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
-
Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle PROTAC Linkers Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
|
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 1644644-96-1
-
Appearance Solid
-
Molecular Weight 327.29
-
Formel C15H13N5O4
-
Color Purple to purplish red
-
SMILES
O=C(ON1C(CCC1=O)=O)CC2=CC=C(C3=NN=C(C)N=N3)C=C2
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (305.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
-
Data Sheet (271 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0554 mL | 15.2770 mL | 30.5539 mL | 76.3849 mL |
| 5 mM | 0.6111 mL | 3.0554 mL | 6.1108 mL | 15.2770 mL | |
| 10 mM | 0.3055 mL | 1.5277 mL | 3.0554 mL | 7.6385 mL | |
| 15 mM | 0.2037 mL | 1.0185 mL | 2.0369 mL | 5.0923 mL | |
| 20 mM | 0.1528 mL | 0.7638 mL | 1.5277 mL | 3.8192 mL | |
| 25 mM | 0.1222 mL | 0.6111 mL | 1.2222 mL | 3.0554 mL | |
| 30 mM | 0.1018 mL | 0.5092 mL | 1.0185 mL | 2.5462 mL | |
| 40 mM | 0.0764 mL | 0.3819 mL | 0.7638 mL | 1.9096 mL | |
| 50 mM | 0.0611 mL | 0.3055 mL | 0.6111 mL | 1.5277 mL | |
| 60 mM | 0.0509 mL | 0.2546 mL | 0.5092 mL | 1.2731 mL | |
| 80 mM | 0.0382 mL | 0.1910 mL | 0.3819 mL | 0.9548 mL | |
| 100 mM | 0.0306 mL | 0.1528 mL | 0.3055 mL | 0.7638 mL |
Methyltetrazine-Ph-NHS ester Related Classifications
HY-130283 Related Classifications
Powered by Bioz