Methyltetrazine-Maleimide
Based on 1 Customer Validation
Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyltetrazine-Maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- Reinheit: 98.12%
- Formel: C17H16N6O3
- Molecular Weight:352.35
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 352.35
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Formel C17H16N6O3
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Color Dark purple to black
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SMILES
CC(N=N1)=NN=C1C2=CC=C(CNC(CCN3C(C=CC3=O)=O)=O)C=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (283.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.8381 mL | 14.1904 mL | 28.3809 mL | 70.9522 mL |
| 5 mM | 0.5676 mL | 2.8381 mL | 5.6762 mL | 14.1904 mL | |
| 10 mM | 0.2838 mL | 1.4190 mL | 2.8381 mL | 7.0952 mL | |
| 15 mM | 0.1892 mL | 0.9460 mL | 1.8921 mL | 4.7301 mL | |
| 20 mM | 0.1419 mL | 0.7095 mL | 1.4190 mL | 3.5476 mL | |
| 25 mM | 0.1135 mL | 0.5676 mL | 1.1352 mL | 2.8381 mL | |
| 30 mM | 0.0946 mL | 0.4730 mL | 0.9460 mL | 2.3651 mL | |
| 40 mM | 0.0710 mL | 0.3548 mL | 0.7095 mL | 1.7738 mL | |
| 50 mM | 0.0568 mL | 0.2838 mL | 0.5676 mL | 1.4190 mL | |
| 60 mM | 0.0473 mL | 0.2365 mL | 0.4730 mL | 1.1825 mL | |
| 80 mM | 0.0355 mL | 0.1774 mL | 0.3548 mL | 0.8869 mL | |
| 100 mM | 0.0284 mL | 0.1419 mL | 0.2838 mL | 0.7095 mL |
Methyltetrazine-Maleimide Related Classifications
HY-136104 Related Classifications
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