Tetrazine-PEG4-amine hydrochloride
Based on 1 Customer Validation
Tetrazine-PEG4-amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tetrazine-PEG4-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
For research use only. We do not sell to patients.
- Purity: 99.83%
- CAS No.: 2752945-36-9
- Formula: C20H31ClN6O5
- Molecular Weight:470.95
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2752945-36-9
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Appearance Solid
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Molecular Weight 470.95
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Formula C20H31ClN6O5
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Color Red to purplish red
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SMILES
NCCOCCOCCOCCOCCC(NCC1=CC=C(C2=NN=CN=N2)C=C1)=O.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
Methanol : 250 mg/mL (530.84 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Methanol | 1 mM | 2.1234 mL | 10.6168 mL | 21.2337 mL | 53.0842 mL |
| 5 mM | 0.4247 mL | 2.1234 mL | 4.2467 mL | 10.6168 mL | |
| 10 mM | 0.2123 mL | 1.0617 mL | 2.1234 mL | 5.3084 mL | |
| 15 mM | 0.1416 mL | 0.7078 mL | 1.4156 mL | 3.5389 mL | |
| 20 mM | 0.1062 mL | 0.5308 mL | 1.0617 mL | 2.6542 mL | |
| 25 mM | 0.0849 mL | 0.4247 mL | 0.8493 mL | 2.1234 mL | |
| 30 mM | 0.0708 mL | 0.3539 mL | 0.7078 mL | 1.7695 mL | |
| 40 mM | 0.0531 mL | 0.2654 mL | 0.5308 mL | 1.3271 mL | |
| 50 mM | 0.0425 mL | 0.2123 mL | 0.4247 mL | 1.0617 mL | |
| 60 mM | 0.0354 mL | 0.1769 mL | 0.3539 mL | 0.8847 mL | |
| 80 mM | 0.0265 mL | 0.1327 mL | 0.2654 mL | 0.6636 mL | |
| 100 mM | 0.0212 mL | 0.1062 mL | 0.2123 mL | 0.5308 mL |
Tetrazine-PEG4-amine hydrochloride Related Classifications
HY-130977 Related Classifications
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