UDP-Galactose disodium
Based on 5 publication(s) in Google Scholar
UDP-Galactose disodium is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose disodium is the natural agonist of the P2Y14 receptor coupled to Gi proteins in the immune system (IC50 = 0.67 μM, hP2Y14). UDP-Galactose disodium can be used to study cell signal transduction and substance metabolism.
For research use only. We do not sell to patients.
- Purity: 99.73%
- CAS No.: 137868-52-1
- Formula: C15H22N2Na2O17P2
- Molecular Weight:610.27
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) UDP-Galactose disodium
MoreAll Endogenous Metabolite Isoforms
MoreAll P2Y Receptor Isoforms
More
Biological Activity
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P2Y14 Receptor 0.67 μM (EC50) |
UDP-Galactose (2 mM) disodium restores UDP-galactose transport in the endoplasmic reticulum of GalT-1/UGT-CHOlec8 cells[2].
UDP-galactose disodium is transported via the endoplasmic reticulum to support GalCer synthesis in GalT-1/UGT-CHOlec8 cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 137868-52-1
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Appearance Solid
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Molecular Weight 610.27
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Formula C15H22N2Na2O17P2
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Color White to off-white
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SMILES
O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(O[C@@H]3[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)(O[Na])=O)(O[Na])=O)O2)NC1=O
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (5)
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Journal Impact Factor
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Most Recent
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Mol Plant
2025 Dec 13:S1674-2052(25)00435-6. PMID: 41392480 -
Cell Rep
Blocking glycogen synthase 1 in white adipose tissue alleviates hypermetabolism following severe burn injury through inhibition of JAK2 by UDPG. [Abstract]2025 Nov 18;44(12):116577. PMID: 41259203 -
J Exp Bot
Diel carbon buffering by floridoside enables source-sink resilience in the intertidal red alga Pyropia haitanensis. [Abstract]2026 Apr 17:erag189. PMID: 41999048 -
J Biotechnol
Rational design of a bifunctional glycosyltransferase for enhanced substrate promiscuity and thermostability. [Abstract]2025 Dec 19:410:285-297. PMID: 41422993 -
Solvent & Solubility
H2O : 250 mg/mL (409.65 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Ko H, et al. Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J Med Chem. 2007 May 3;50(9):2030-9. [Content Brief]
[2]. Sprong H, et al. Association of the Golgi UDP-galactose transporter with UDP-galactose:ceramide galactosyltransferase allows UDP-galactose import in the endoplasmic reticulum. Mol Biol Cell. 2003;14(8):3482-3493. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.6386 mL | 8.1931 mL | 16.3862 mL | 40.9655 mL |
| 5 mM | 0.3277 mL | 1.6386 mL | 3.2772 mL | 8.1931 mL | |
| 10 mM | 0.1639 mL | 0.8193 mL | 1.6386 mL | 4.0965 mL | |
| 15 mM | 0.1092 mL | 0.5462 mL | 1.0924 mL | 2.7310 mL | |
| 20 mM | 0.0819 mL | 0.4097 mL | 0.8193 mL | 2.0483 mL | |
| 25 mM | 0.0655 mL | 0.3277 mL | 0.6554 mL | 1.6386 mL | |
| 30 mM | 0.0546 mL | 0.2731 mL | 0.5462 mL | 1.3655 mL | |
| 40 mM | 0.0410 mL | 0.2048 mL | 0.4097 mL | 1.0241 mL | |
| 50 mM | 0.0328 mL | 0.1639 mL | 0.3277 mL | 0.8193 mL | |
| 60 mM | 0.0273 mL | 0.1366 mL | 0.2731 mL | 0.6828 mL | |
| 80 mM | 0.0205 mL | 0.1024 mL | 0.2048 mL | 0.5121 mL | |
| 100 mM | 0.0164 mL | 0.0819 mL | 0.1639 mL | 0.4097 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
UDP-Galactose disodium Related Classifications
HY-114364 Related Classifications
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