UDP-Galactose
Based on 5 publication(s) in Google Scholar
UDP-Galactose is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose is the natural agonist of the P2Y14 receptor coupled to Gi proteins in the immune system (IC50 = 0.67 μM, hP2Y14). UDP-Galactose can be used to study cell signal transduction and substance metabolism.
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- CAS No.: 2956-16-3
- Formule: C15H24N2O17P2
- Masse moléculaire:566.30
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) UDP-Galactose
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Activité biologique
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Human Endogenous Metabolite |
P2Y14 Receptor 0.67 μM (EC50) |
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Cell Line
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Type | Value | Description | References |
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| COS-7 | EC50 |
0.67 μM
Compound: 2
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Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysis
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysis
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[PMID: 17407275] |
| COS-7 | EC50 |
0.67 μM
Compound: 7
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Agonist activity at human P2Y14 receptor expressed in human COS7 cells
Agonist activity at human P2Y14 receptor expressed in human COS7 cells
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[PMID: 19502066] |
UDP-Galactose (2 mM) restores UDP-galactose transport in the endoplasmic reticulum of GalT-1/UGT-CHOlec8 cells[2].
UDP-galactose is transported via the endoplasmic reticulum to support GalCer synthesis in GalT-1/UGT-CHOlec8 cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2956-16-3
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Masse moléculaire 566.30
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Formule C15H24N2O17P2
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SMILES
O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(O[C@@H]3[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)(O)=O)(O)=O)O2)NC1=O
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (5)
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Journal Impact Factor
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Most Recent
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Mol Plant
2025 Dec 13:S1674-2052(25)00435-6. PMID: 41392480 -
Cell Rep
Blocking glycogen synthase 1 in white adipose tissue alleviates hypermetabolism following severe burn injury through inhibition of JAK2 by UDPG. [Abstract]2025 Nov 18;44(12):116577. PMID: 41259203 -
J Exp Bot
Diel carbon buffering by floridoside enables source-sink resilience in the intertidal red alga Pyropia haitanensis. [Abstract]2026 Apr 17:erag189. PMID: 41999048 -
J Biotechnol
Rational design of a bifunctional glycosyltransferase for enhanced substrate promiscuity and thermostability. [Abstract]2025 Dec 19:410:285-297. PMID: 41422993 -
Pureté et documentation
Références
[1].
Ko H, et al. Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J Med Chem. 2007 May 3;50(9):2030-9.
[Content Brief]
[2]. Sprong H, et al. Association of the Golgi UDP-galactose transporter with UDP-galactose:ceramide galactosyltransferase allows UDP-galactose import in the endoplasmic reticulum. Mol Biol Cell. 2003;14(8):3482-3493. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UDP-Galactose Related Classifications
HY-150524 Related Classifications
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