2956-16-3
Chemical Structure
UDP-Galactose
- CAS No.: 2956-16-3
- Formula:C15H24N2O17P2
- Molecular Weight:566.30
IUPAC Name: methyl (2S,4S)-1-benzyl-4-fluoropyrrolidine-2-carboxylate
InChIKey: HSCJRCZFDFQWRP-ABVWGUQPSA-N
SMILES: O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(O[C@@H]3[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)(O)=O)(O)=O)O2)NC1=O
Biological Activity: UDP-Galactose is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose is the natural agonist of the P2Y14 receptor coupled to Gi proteins in the immune system (IC50 = 0.67 μM, hP2Y14). UDP-Galactose can be used to study cell signal transduction and substance metabolism[1][2].
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UDP-Galactose | UDP-Galactose is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose is the natural agonist of the P2Y14 receptor coupled to Gi proteins in the immune system (IC50 = 0.67 μM, hP2Y14). UDP-Galactose can be used to study cell signal transduction and substance metabolism. | |||||||||||||||||||||
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References
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[1]. Ko H, et al. Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J Med Chem. 2007 May 3;50(9):2030-9.
[Content Brief] - [2]. Sprong H, et al. Association of the Golgi UDP-galactose transporter with UDP-galactose:ceramide galactosyltransferase allows UDP-galactose import in the endoplasmic reticulum. Mol Biol Cell. 2003;14(8):3482-3493. [Content Brief]
