1. GPCR/G Protein
  2. Adenylate Cyclase
  3. Guanylyl Imidodiphosphate trisodium

Guanylyl Imidodiphosphate trisodium (Synonyms: Guanosine 5'-[β,γ-imido]triphosphate trisodium)

Cat. No.: HY-100767
Handling Instructions

Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies.

For research use only. We do not sell to patients.

Guanylyl Imidodiphosphate trisodium Chemical Structure

Guanylyl Imidodiphosphate trisodium Chemical Structure

CAS No. : 148892-91-5

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Description

Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies[1][2][3].

In Vitro

Guanylyl Imidodiphosphate trisodium (GppNHp) (100 μM) induces the secretion of dense granules from permeabilized platelets in response to calcium ion stimulation, and GTP-Ral enhances the calcium sensitivity of permeabilized platelet dense granule secretion which is inhibited by Sec5-RBD[1].
Guanylyl Imidodiphosphate trisodium (GppNHp) (0.017-333 μM) causes a significant reduction in the lag time required to stimulate adenylate cyclase activity[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

591.16

Formula

C10H17N6Na3O13P3

CAS No.
SMILES

O[[email protected]]1[[email protected]](O[[email protected]@H]([[email protected]]1O)COP(OP(NP(O)(O)=O)(O)=O)(O)=O)([H])N2C3=C(C(N=C(N3)N)=O)N=C2.[Na].[Na].[Na]

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Guanylyl Imidodiphosphate trisodium
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HY-100767
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