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KH7 

Cat. No.: HY-103194 Purity: >99.0%
Handling Instructions

KH7 is a soluble adenylyl cyclase (sAC)-specific inhibitor, with IC50s of 3-10 μM toward both recombinant purified human sACt protein and heterologously expressed sACt in cellular assays.

For research use only. We do not sell to patients.

KH7 Chemical Structure

KH7 Chemical Structure

CAS No. : 330676-02-3

Size Price Stock Quantity
5 mg USD 140 In-stock
Estimated Time of Arrival: December 31
10 mg USD 220 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

KH7 is a soluble adenylyl cyclase (sAC)-specific inhibitor, with IC50s of 3-10 μM toward both recombinant purified human sACt protein and heterologously expressed sACt in cellular assays[1].

IC50 & Target

IC50: 3-10 μM (recombinant sACt)[1].

Molecular Weight

419.30

Formula

C₁₇H₁₅BrN₄O₂S

CAS No.

330676-02-3

SMILES

CC(SC1=NC2=CC=CC=C2N1)C(N/N=C/C3=CC(Br)=CC=C3O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (238.49 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3849 mL 11.9246 mL 23.8493 mL
5 mM 0.4770 mL 2.3849 mL 4.7699 mL
10 mM 0.2385 mL 1.1925 mL 2.3849 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (5.96 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: >99.0%

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Product Name:
KH7
Cat. No.:
HY-103194
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