148892-91-5
Chemical Structure
Guanylyl Imidodiphosphate trisodium
Synonym(s): Guanosine 5'-[β,γ-imido]triphosphate trisodium
- CAS No.: 148892-91-5
- Formula:C10H14N6Na3O13P3
- Molecular Weight:588.14
InChIKey: QGJNRMUNXAROIT-CYCLDIHTSA-K
SMILES: O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(NP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O3)=C2N=C(N)N1
Biological Activity: Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies[1][2][3].
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Guanylyl Imidodiphosphate trisodium | 96.72% | Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies. | ||||||||||||||||||||
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- [1]. Mitsunori Kawato, et al. Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway. J Biol Chem. 2008 Jan 4;283(1):166-174. [Content Brief]
- [2]. J Goldberg, et al. Structural basis for activation of ARF GTPase: mechanisms of guanine nucleotide exchange and GTP-myristoyl switching. Cell. 1998 Oct 16;95(2):237-48. [Content Brief]
- [3]. C Gaudin, et al. Overexpression of Gs alpha protein in the hearts of transgenic mice. J Clin Invest. 1995 Apr;95(4):1676-83. [Content Brief]
Keywords