Deoxythymidine-5'-triphosphate trisodium solution (100 mM)  (Synonyms: dTTP trisodium solution (100 mM))

Deoxythymidine-5'-triphosphate (dTTP) (trisodium) solution (100 mM) is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. Deoxythymidine-5'-triphosphate (trisodium) solution (100 mM) is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied as an aqueous solution.

Deoxythymidine-5'-triphosphate (trisodium) solution (100 mM) serves as one of the key variables in optimizing PCR amplification strategies for long-fragment, high A+T content mitochondrial DNA: increasing the concentrations of dATP and dTTP while decreasing those of dGTP and dCTP in the PCR reaction system is critical for the successful amplification of long-fragment (>2.0 kb) DNA with high A+T content^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

548.11

C₁₀H₁₄N₂Na₃O₁₄P₃

27821-54-1

Liquid

Colorless to light yellow

O[C@H]([C@H](O1)COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)C[C@@H]1N(C2=O)C=C(C(N2)=O)C

Room temperature in continental US; may vary elsewhere.

Solution, -20°C, 2 years

• [1]. Rondan Dueñas JC, et al. Specific requirements for PCR amplification of long mitochondrial A+T-rich DNA. Biotechniques. 1999 Aug;27(2):258-60.
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