3056945-59-3
Chemical Structure
N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM)
Synonym(s): 1-Methylpseudouridine-5′-triphosphate trisodium; N1-Me-Pseudo UTP trisodium; N1-Methyl-Pseudo-UTP trisodium
- CAS No.: 3056945-59-3
- Formula:C10H14N2Na3O15P3
- Molecular Weight:564.11
IUPAC Name: 1-(4-methoxyphenyl)prop-2-yn-1-one
InChIKey: NHPNEQMMDVBDAB-PBGPPWEJSA-K
SMILES: O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CN(C)C2=O)O[C@@H]1COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O
Biological Activity:
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability[1].
The product specifications provided below refer solely to the active content of N1-Methylpseudouridine-5′-triphosphate trisodium.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM) | 99.70% | N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability. The product specifications provided below refer solely to the active content of N1-Methylpseudouridine-5′-triphosphate trisodium. |
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Similarity Score 0.77
HY-112582AN1-Methylpseudouridine-5′-triphosphate solution (100 mM) -
Similarity Score 0.71
HY-164767AN1-Methyl-2'-O-Methylpseudo-UTP -
Similarity Score 0.69
HY-178571N1-Me-pUMP -
Similarity Score 0.67
HY-107372AUridine triphosphate trisodium dihydrate -
Similarity Score 0.67
HY-W013715BDeoxythymidine-5'-triphosphate trisodium,100 mM Solution,PCR Grade -
Similarity Score 0.65
HY-141567Pseudouridine 5'-triphosphate -
Similarity Score 0.64
HY-115740ACytarabine triphosphate trisodium -
Similarity Score 0.64
HY-125818DCytidine-5'-triphosphate trisodium -
Similarity Score 0.63
HY-107372HUTP trisodium salt, 100 mM Solution, PCR Grade -
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References
- [1]. Andries O, Mc Cafferty S, De Smedt SC, Weiss R, Sanders NN, Kitada T. N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice. J Control Release. 2015;217:337-344. [Content Brief]
