1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. Deoxyguanosine triphosphate trisodium salt

Deoxyguanosine triphosphate trisodium salt  (Synonyms: dGTP trisodium salt; 2'-Deoxyguanosine-5'-triphosphate trisodium salt)

Cat. No.: HY-W008661 Purity: 99.15%
COA Handling Instructions

Deoxyguanosine triphosphate (dGTP) trisodium salt is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.

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Deoxyguanosine triphosphate trisodium salt Chemical Structure

Deoxyguanosine triphosphate trisodium salt Chemical Structure

CAS No. : 93919-41-6

Size Price Stock Quantity
Solvent
25mg (100 mM * 436 μL in Water) USD 70 In-stock
Solvent
50mg (100 mM * 872 μL in Water) USD 100 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Deoxyguanosine triphosphate (dGTP) trisodium salt is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification[1].

Molecular Weight

573.13

Formula

C10H13N5Na3O13P3

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O[C@H]([C@H](O1)COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)C[C@@H]1N(C=N2)C(NC(N)=N3)=C2C3=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Solvent & Solubility
In Vitro: 

H2O : 66.67 mg/mL (116.33 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (174.48 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.15%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7448 mL 8.7240 mL 17.4480 mL 43.6201 mL
5 mM 0.3490 mL 1.7448 mL 3.4896 mL 8.7240 mL
10 mM 0.1745 mL 0.8724 mL 1.7448 mL 4.3620 mL
15 mM 0.1163 mL 0.5816 mL 1.1632 mL 2.9080 mL
20 mM 0.0872 mL 0.4362 mL 0.8724 mL 2.1810 mL
25 mM 0.0698 mL 0.3490 mL 0.6979 mL 1.7448 mL
30 mM 0.0582 mL 0.2908 mL 0.5816 mL 1.4540 mL
40 mM 0.0436 mL 0.2181 mL 0.4362 mL 1.0905 mL
50 mM 0.0349 mL 0.1745 mL 0.3490 mL 0.8724 mL
60 mM 0.0291 mL 0.1454 mL 0.2908 mL 0.7270 mL
80 mM 0.0218 mL 0.1091 mL 0.2181 mL 0.5453 mL
100 mM 0.0174 mL 0.0872 mL 0.1745 mL 0.4362 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Deoxyguanosine triphosphate trisodium salt Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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