2′-Deoxy-GDP trisodium
Based on 1 Customer Validation
2′-Deoxy-GDP (dGDP) trisodium, a guanosine monophosphate (GMP) analogue, is a hypoxanthine phosphoribosyltransferase (HGPRT) inhibitor with an IC50 of 12.5 μM. HGPRT is a central enzyme in the purine recycling pathway of all protozoan parasites.
For research use only. We do not sell to patients.
- Purity: 98.78%
- CAS No.: 102783-74-4
- Formula: C10H12N5Na3O10P2
- Molecular Weight:493.15
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All Parasite Isoforms
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Biological Activity
Chemical Information
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CAS No. 102783-74-4
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Appearance Solid
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Molecular Weight 493.15
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Formula C10H12N5Na3O10P2
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Color White to off-white
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SMILES
O[C@H]1C[C@H](N(C=N2)C3=C2C(N=C(N)N3)=O)O[C@@H]1COP(OP(O[Na])(O[Na])=O)(O[Na])=O
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Synonyms
dGDP trisodium; 2'-Deoxyguanosine-5'-diphosphate trisodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
H2O : 50 mg/mL (101.39 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.0278 mL | 10.1389 mL | 20.2778 mL | 50.6945 mL |
| 5 mM | 0.4056 mL | 2.0278 mL | 4.0556 mL | 10.1389 mL | |
| 10 mM | 0.2028 mL | 1.0139 mL | 2.0278 mL | 5.0695 mL | |
| 15 mM | 0.1352 mL | 0.6759 mL | 1.3519 mL | 3.3796 mL | |
| 20 mM | 0.1014 mL | 0.5069 mL | 1.0139 mL | 2.5347 mL | |
| 25 mM | 0.0811 mL | 0.4056 mL | 0.8111 mL | 2.0278 mL | |
| 30 mM | 0.0676 mL | 0.3380 mL | 0.6759 mL | 1.6898 mL | |
| 40 mM | 0.0507 mL | 0.2535 mL | 0.5069 mL | 1.2674 mL | |
| 50 mM | 0.0406 mL | 0.2028 mL | 0.4056 mL | 1.0139 mL | |
| 60 mM | 0.0338 mL | 0.1690 mL | 0.3380 mL | 0.8449 mL | |
| 80 mM | 0.0253 mL | 0.1267 mL | 0.2535 mL | 0.6337 mL | |
| 100 mM | 0.0203 mL | 0.1014 mL | 0.2028 mL | 0.5069 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.